STX16

Description		syntaxin 16
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Endomembrane System Membrane Synaptic Vesicle Membrane SNARE Complex Golgi Cisterna Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Vesicle Docking
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases		Pseudohypoparathyroidism
GWAS		Cardiovascular risk factors (age interaction) ( 20838585) Hemoglobin ( 32888494)
Novel Interacting Genes		13 novel interacting genes: DOCK1 MEOX2 NAPB PTPN12 RHOU STX1A STX2 STX4 STX6 VAMP3 VAMP4 VPS45 VTI1A
Interacting Genes		13 interacting genes: DOCK1 MEOX2 NAPB PTPN12 RHOU STX1A STX2 STX4 STX6 VAMP3 VAMP4 VPS45 VTI1A
Entrez ID		8675
HPRD ID		04718
Ensembl ID		ENSG00000124222
Uniprot IDs		B4DJX9 O14662
PDB IDs		8QQF
Enriched GO Terms of Interacting Partners?		SNARE Complex SNAP Receptor Activity Organelle Fusion Vesicle-mediated Transport Vesicle Fusion Organelle Membrane Fusion SNARE Complex Assembly Vesicle Docking SNARE Binding Membrane Fusion Vesicle Organization Intracellular Protein Transport Organelle Localization By Membrane Tethering Membrane Docking Protein Transport Intracellular Transport Endomembrane System Establishment Of Protein Localization Membrane Organization Cellular Localization Establishment Of Localization In Cell Phagocytic Vesicle Intracellular Protein Localization Trans-Golgi Network Membrane Synaptic Vesicle To Endosome Fusion Vesicle-mediated Transport To The Plasma Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Cornified Envelope Assembly Endosome Exocytosis Organelle Localization Cellular Response To Type II Interferon Endocytic Recycling Clathrin-coated Vesicle Regulation Of Synaptic Vesicle Priming Localization Within Membrane Endosomal Transport Glutamatergic Synapse Golgi Vesicle Transport Retrograde Transport, Endosome To Golgi Response To Type II Interferon Post-Golgi Vesicle-mediated Transport Golgi Membrane Bounding Membrane Of Organelle Cytosolic Transport Synaptic Vesicle Organelle Organization Secretion By Cell Presynaptic Active Zone Membrane Calcium-ion Regulated Exocytosis
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