LY6D and ARFIP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		LY6D	ARFIP2
Description		lymphocyte antigen 6 family member D	ARF interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Cell Surface Membrane Side Of Membrane	Ruffle Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cell Cortex Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity
	Biological Process	Cell Adhesion Lymphocyte Differentiation Response To Stilbenoid	Mitophagy Intracellular Protein Transport Autophagy Small GTPase-mediated Signal Transduction Intracellular Protein Localization Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Phagophore Assembly Site
Pathways		Post-translational modification: synthesis of GPI-anchored proteins	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Malaria ( 31844061)
Interacting Genes		7 interacting genes: ABCB11 AQP6 ARFIP2 ELOVL4 PKIB TMEM31 TMEM86B	62 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 BLOC1S2 C19orf25 CDKN2A CDR1 CEP63 CMTM5 CYTH3 DGAT2L6 DMAP1 DTNBP1 FADS6 FSD2 GOLGA2 GSG1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 KRT16 LNX1 LY6D MAL2 MIEF1 MIEF2 NDRG4 NFE2L2 NRDE2 NUP62 PBX3 PKNOX2 PLP2 PPIF PUM3 RAC1 RAC2 RAC3 REEP5 REL RND1 SCAMP1 SCAMP5 SDCBP SH3GLB1 SMG9 SNX1 SOCS2 STAT3 SYP TMEM255B TRIM54 TTPA USHBP1
Entrez ID		8581	23647
HPRD ID		09370	07209
Ensembl ID		ENSG00000167656	ENSG00000132254
Uniprot IDs		Q14210	A0A087X1E4 B4DUZ3 B4DXH2 P53365
PDB IDs			1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Canalicular Bile Acid Transmembrane Transporter Activity Positive Regulation Of Bile Acid Secretion Canalicular Bile Acid Transport D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Intracellular Canaliculus Regulation Of Bile Acid Secretion ABC-type Bile Acid Transporter Activity Membrane Curvature Sensor Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Intercellular Canaliculus Monoatomic Anion Channel Activity Renal Water Transport Fatty Acid Elongation, Saturated Fatty Acid Ammonium Transmembrane Transport Ammonium Channel Activity CAMP-dependent Protein Kinase Inhibitor Activity Carboxylic Acid Biosynthetic Process G Protein-coupled Photoreceptor Activity Bile Acid Transmembrane Transporter Activity Regulation Of Bile Acid Metabolic Process Water Channel Activity Carbon Dioxide Transport Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Fatty Acid Metabolic Process Xenobiotic Export From Cell ABC-type Xenobiotic Transporter Activity Xenobiotic Transmembrane Transport Phosphatidylcholine Acyl-chain Remodeling Phospholipid Homeostasis Regulation Of Fatty Acid Beta-oxidation Protein Localization To Phagophore Assembly Site Lipid Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Bile Acid And Bile Salt Transport GTP-dependent Protein Binding Ether Lipid Metabolic Process	Regulation Of Vesicle-mediated Transport Regulation Of Cellular Component Organization Vesicle-mediated Transport Regulation Of Transport Regulation Of Endocytosis GTPase Activity Cellular Localization Protein Binding Protein Transport Regulation Of Receptor-mediated Endocytosis GTP Binding Positive Regulation Of Transport Positive Regulation Of Cellular Component Organization Establishment Of Protein Localization Organelle Organization Regulation Of Postsynapse Organization Cerebral Cortex GABAergic Interneuron Development Intracellular Transport Regulation Of Organelle Organization Regulation Of Cellular Localization Membrane Organization Positive Regulation Of Establishment Of Protein Localization Intracellular Protein Transport Cortical Cytoskeleton Organization Regulation Of Hydrogen Peroxide Metabolic Process NADPH Oxidase Complex Intracellular Protein Localization PTB Domain Binding Regulation Of Dendritic Spine Development Respiratory Burst Lamellipodium Golgi Vesicle Transport Establishment Of Localization In Cell Positive Regulation Of Secretion By Cell Regulation Of Synapse Organization Negative Regulation Of Endocytosis Regulation Of Establishment Of Protein Localization Regulation Of Cytoskeleton Organization Synaptic Vesicle Membrane Erythrocyte Enucleation Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Secretion Regulation Of Receptor Internalization Postsynapse Cytoskeleton Organization Negative Regulation Of Receptor-mediated Endocytosis Endocytosis Protein Kinase Binding Intracellular Signaling Cassette Positive Regulation Of Mitotic Cytokinetic Process
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