MICALL1 and RAB1A

Number of citations of the paper that reports this interaction (PubMedID 12788069)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MICALL1	RAB1A
Description		MICAL like 1	RAB1A, member RAS oncogene family
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GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Late Endosome Trans-Golgi Network Centriole Cytoskeleton Plasma Membrane Adherens Junction Cilium Cytoplasmic Side Of Endosome Membrane Membrane Late Endosome Membrane Cell Projection Recycling Endosome Membrane Ciliary Membrane	Golgi Membrane Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Membrane Transport Vesicle Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Cytoskeletal Anchor Activity Protein-macromolecule Adaptor Activity Small GTPase Binding Identical Protein Binding Cadherin Binding Metal Ion Binding Phosphatidic Acid Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Cadherin Binding Metal Ion Binding
	Biological Process	Cell Migration Involved In Sprouting Angiogenesis Protein Targeting To Membrane Endocytosis Receptor-mediated Endocytosis Protein Transport Neuron Projection Development Endocytic Recycling Slow Endocytic Recycling Protein Localization To Endosome Cilium Assembly Protein Localization To Cilium Plasma Membrane Tubulation Plasma Membrane Bounded Cell Projection Organization	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Protein Transport Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Positive Regulation Of Interleukin-8 Production Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Vesicle Transport Along Microtubule Cilium Assembly COPII-coated Vesicle Cargo Loading Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 30598549) Platelet count ( 32888494) Platelet distribution width ( 27863252 32888494)	High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Triglyceride levels ( 32154731)
Interacting Genes		6 interacting genes: RAB13 RAB1A RFFL YWHAB YWHAG ZP3	35 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D EBP FNDC3B FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 MTOR OCRL PLK1 PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RFK RUSC2 SLC16A8 SNCA SNRNP27 SNRPG SSX2IP SYT5 TBC1D17 USO1 ZNF593
Entrez ID		85377	5861
HPRD ID		11363	01538
Ensembl ID		ENSG00000100139	ENSG00000138069
Uniprot IDs		A0A7P0T9P2 B0QY86 B0QY91 Q8N3F8	B7Z8M7 P62820 Q5U0I6
PDB IDs		2KSP	2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS 7EQ2 9MHF 9MHG 9MHH
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Intracellular Protein Localization Protein Sequestering Activity Trans-Golgi Network To Recycling Endosome Transport Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Type IV Hypersensitivity Positive Regulation Of Antral Ovarian Follicle Growth Melanosome Cellular Response To Insulin Stimulus Recycling Endosome Membrane Regulation Of T Cell Mediated Immunity Epithelial Cell Development Positive Regulation Of Immune Response Response To Insulin Protein Localization To Cell Leading Edge Establishment Of Sertoli Cell Barrier Regulation Of TOR Signaling Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Protein Kinase C Inhibitor Activity Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Positive Regulation Of Acrosomal Vesicle Exocytosis Positive Regulation Of Ovarian Follicle Development Egg Coat Formation Acrosin Binding Negative Regulation Of Binding Of Sperm To Zona Pellucida Structural Constituent Of Egg Coat Egg Coat Regulation Of Type IV Hypersensitivity Regulation Of Acrosomal Vesicle Exocytosis Endosome Cellular Response To Peptide Hormone Stimulus Regulation Of Binding Of Sperm To Zona Pellucida Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Ovarian Follicle Development Growth Hormone Secretion Insulin-responsive Compartment Protein Targeting Phosphoserine Residue Binding Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Cell Development Regulation Of Adaptive Immune Response Extracellular Exosome Protein Domain Specific Binding Positive Regulation Of Hypersensitivity Virion Assembly Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Acrosome Reaction Regulation Of Immune Response	Rab-protein Geranylgeranyltransferase Complex Protein Geranylgeranylation Small GTPase Binding Golgi Organization Protein Prenylation Vesicle-mediated Transport Organelle Organization Golgi Vesicle Transport Rab Geranylgeranyltransferase Activity Protein Geranylgeranyltransferase Activity Protein Prenyltransferase Activity Cytoplasm Organelle Assembly Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Protein Localization To Cytoskeleton Centrosome Cycle Cis-Golgi Network Establishment Of Localization In Cell Prenyltransferase Activity Protein Destabilization Cytoplasmic Vesicle Protein Localization To Cilium Spindle Organization Cytosol Ciliary Basal Body Cadherin Binding Intracellular Transport Behavioral Response To Cocaine Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Microtubule Organizing Center Organization Positive Regulation Of Protein-containing Complex Assembly Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Vesicle Fusion Establishment Of Protein Localization Cell Projection Assembly Spindle Assembly Protein Serine/threonine Kinase Binding Protein Localization To Organelle GTPase Activator Activity Chemotaxis To Arachidonate Regulation Of Protein-containing Complex Assembly Microtubule Nucleation Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cilium Assembly Cellular Component Assembly Protein Localization To Centrosome Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Lamellipodium Assembly Regulation Of Organelle Assembly
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