FKBP6 and RAB11FIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FKBP6	RAB11FIP2
Description		FKBP prolyl isomerase family member 6 (inactive)	RAB11 family interacting protein 2
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GO Annotations	Cellular Component	Synaptonemal Complex Fibrillar Center Nucleus Cytoplasm Cytosol Microtubule Cytoskeleton Intercellular Bridge	Phagocytic Cup Nucleoplasm Endosome Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cell Projection Recycling Endosome Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding	Protein Binding Protein Kinase Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Protein Folding Spermatogenesis Cell Differentiation Regulatory NcRNA-mediated Gene Silencing PiRNA Processing Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle Transposable Element Silencing By PiRNA-mediated DNA Methylation	Phagocytosis Cell Communication Protein Transport Vesicle-mediated Transport Signaling Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS		Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 29403010 30993211)
Interacting Genes		38 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CFTR CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 RAB11FIP2 RNF4 SAXO4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655	23 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B OGT PDZD11 PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 SNCA YWHAE YWHAG
Entrez ID		8468	22841
HPRD ID		05326	10548
Ensembl ID		ENSG00000077800	ENSG00000107560
Uniprot IDs		O75344	Q7L804
PDB IDs		3B7X	2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?		Shelterin Complex Telomere Assembly Meiotic DNA Double-strand Break Formation Protein Binding Regulation Of Telomere Maintenance Via Telomerase Nuclear Telomere Cap Complex Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Chromosome, Telomeric Region	Vesicle-mediated Transport Endosomal Transport Endocytosis Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Import Into Cell Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Intracellular Transport Myosin V Binding Organelle Localization Establishment Of Protein Localization Regulation Of Endocytic Recycling Endocytic Recycling Regulation Of Biological Quality Vesicle-mediated Transport In Synapse Exocytosis Recycling Endosome Membrane Cellular Localization Secretion By Cell Establishment Of Vesicle Localization Protein Localization To Organelle Synaptic Vesicle Endocytosis Vesicle Localization Protein Sequestering Activity Regulation Of Intracellular Transport Presynaptic Endocytosis Synaptic Vesicle Membrane Synaptic Vesicle Amyloid-beta Clearance By Transcytosis Regulation Of Synapse Organization Secretion Protein Transport Cytoplasm Regulation Of Cellular Localization Positive Regulation Of Endocytosis Postsynaptic Endocytic Zone Glutamatergic Synapse Receptor-mediated Endocytosis GTP Binding Receptor Internalization Regulation Of Transport Clathrin-coated Pit G Protein Activity Regulation Of Protein Localization Protein-macromolecule Adaptor Activity Regulation Of SNARE Complex Assembly Phagocytic Vesicle Protein Localization To Endoplasmic Reticulum
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