RAB11FIP2 and PDZD11

		RAB11FIP2	PDZD11
Description		RAB11 family interacting protein 2	PDZ domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Endosome Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Cell Projection Recycling Endosome Membrane	Extracellular Region Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Membrane Basolateral Plasma Membrane Pore Complex Anchoring Junction Presynapse
	Molecular Function	Protein Binding Protein Kinase Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Phagocytosis Cell Communication Protein Transport Vesicle-mediated Transport Signaling Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane	Neurotransmitter Secretion Regulation Of Synaptic Assembly At Neuromuscular Junction Pore Complex Assembly Synaptic Vesicle Transport
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 29403010 30993211)
Interacting Genes		23 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B OGT PDZD11 PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 SNCA YWHAE YWHAG	16 interacting genes: ATP2B2 ATP7A CD79B EDEM1 GDPD2 KIF4A MAGI2 MYO1F NLGN3 RAB11FIP2 SIGMAR1 SMG8 SNX12 TAF1 TEX11 ZMYM3
Entrez ID		22841	51248
HPRD ID		10548	06622
Ensembl ID		ENSG00000107560	ENSG00000120509
Uniprot IDs		Q7L804	Q5EBL8
PDB IDs		2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endosomal Transport Endocytosis Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Import Into Cell Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Recycling Endosome Intracellular Transport Myosin V Binding Organelle Localization Establishment Of Protein Localization Regulation Of Endocytic Recycling Endocytic Recycling Regulation Of Biological Quality Vesicle-mediated Transport In Synapse Exocytosis Recycling Endosome Membrane Cellular Localization Secretion By Cell Establishment Of Vesicle Localization Protein Localization To Organelle Synaptic Vesicle Endocytosis Vesicle Localization Protein Sequestering Activity Regulation Of Intracellular Transport Presynaptic Endocytosis Synaptic Vesicle Membrane Synaptic Vesicle Amyloid-beta Clearance By Transcytosis Regulation Of Synapse Organization Secretion Protein Transport Cytoplasm Regulation Of Cellular Localization Positive Regulation Of Endocytosis Postsynaptic Endocytic Zone Glutamatergic Synapse Receptor-mediated Endocytosis GTP Binding Receptor Internalization Regulation Of Transport Clathrin-coated Pit G Protein Activity Regulation Of Protein Localization Protein-macromolecule Adaptor Activity Regulation Of SNARE Complex Assembly Phagocytic Vesicle Protein Localization To Endoplasmic Reticulum
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