GLYR1 and EIF1AD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		GLYR1	EIF1AD
Description		glyoxylate reductase 1 homolog	eukaryotic translation initiation factor 1A domain containing
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GO Annotations	Cellular Component	Chromatin Nucleosome Nucleus Nucleoplasm Chromosome Cytosol	Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Nucleosome Binding Histone Binding NADP Binding NAD Binding Chromatin-protein Adaptor Activity	RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Transcription Initiation-coupled Chromatin Remodeling Transcription Elongation-coupled Chromatin Remodeling	Translational Initiation
Pathways
Drugs
Diseases
GWAS		Cancer ( 29299148) Night sleep phenotypes ( 27126917)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32271837)
Interacting Genes		15 interacting genes: ARL16 CCNC CDKN2D CFAP206 CLIC3 EIF1AD FHL2 FXR1 GEMIN4 GLIS2 H3-4 H3C1 KDM1A NSD3 NTMT1	34 interacting genes: AP2M1 BEND7 CCDC106 CEP55 CEP76 DPPA2 DRC4 GCSAML GLYR1 GTF2H4 LNX1 MEOX2 MID2 MREG PAX6 PBX4 PICK1 PINX1 RASSF10 RBAK RBM48 SDCBP SDCBP2 STAT1 STX11 TBC1D5 TEPSIN TLE5 TNNI1 ZBTB14 ZBTB8A ZNF280A ZNF521 ZNF558
Entrez ID		84656	84285
HPRD ID		17625	14411
Ensembl ID		ENSG00000140632	ENSG00000175376
Uniprot IDs		Q49A26 Q9NZ78	Q8N9N8
PDB IDs		2UYY 4GUR 4GUS 4GUT 4GUU 4HSU 6R1U 6R25	2DGY 6ZXF 6ZXG 6ZXH
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ribonucleoprotein Complex Binding Chromatin Remodeling Chromatin Organization N-terminal Protein N-methyltransferase Activity N-terminal Protein Amino Acid Methylation Histone Methyltransferase Activity N-terminal Peptidyl-serine Dimethylation N-terminal Peptidyl-proline Dimethylation N-terminal Peptidyl-serine Trimethylation N-terminal Peptidyl-glycine Methylation Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity A Axonemal Microtubule Atrial Cardiac Muscle Cell Development Protein-disulfide Reductase (glutathione) Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Cyclin D2-CDK4 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Translational Initiation Chromosome Structural Constituent Of Chromatin Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone H3K27 Trimethyltransferase Activity	Regulation Of Receptor Internalization Positive Regulation Of Receptor Internalization Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor-mediated Endocytosis AP-2 Adaptor Complex Protein Binding
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