ASCC2 and GTF3C1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	GTF3C1
Description		activating signal cointegrator 1 complex subunit 2	general transcription factor IIIC subunit 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Cytosolic Ribosome RQC-trigger Complex DNA Repair Complex	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex
	Molecular Function	Protein Binding Ubiquitin Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Protein Binding
	Biological Process	DNA Replication DNA Repair DNA Alkylation Repair Regulation Of DNA-templated Transcription DNA Damage Response Ribosome Disassembly Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter RRNA Transcription TRNA Transcription 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		ALKBH3 mediated reversal of alkylation damage ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Asthma ( 31959851) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	25 interacting genes: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 PRPF38A RBM23 SNU13 SUMO2 SUPT5H TBC1D17 UBC UBE3A WEE2-AS1
Entrez ID		84164	2975
HPRD ID		16515	07540
Ensembl ID		ENSG00000100325	ENSG00000077235
Uniprot IDs		Q9H1I8	Q12789
PDB IDs		2DI0 6YXQ	8CLI 8CLJ 8CLK 8CLL
Enriched GO Terms of Interacting Partners?		Macromolecule Metabolic Process Nucleoplasm	Regulation Of Circadian Rhythm
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