CD99L2 and TRAM1L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD99L2	TRAM1L1
Description		CD99 molecule like 2	translocation associated membrane protein 1 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Membrane Anchoring Junction	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cell Adhesion Diapedesis Positive Regulation Of Neutrophil Extravasation Positive Regulation Of T Cell Extravasation	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Transport Protein Insertion Into ER Membrane
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833)	Bipolar disorder ( 33169155) Bronchopulmonary dysplasia ( 23897914) Lateral ventricle volume in trauma-exposed individuals ( 29187748) Metabolite levels ( 23823483) Obesity (extreme) ( 19553259) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		9 interacting genes: CREB3L1 SGTA SGTB SLC30A2 SLC30A8 TMBIM6 TRAM1L1 UBQLN1 UBQLN2	29 interacting genes: ASGR2 BDKRB1 BSCL2 CD53 CD79A CD99L2 CLEC1A CLSTN3 CREB3 CREB3L1 CYBC1 ERGIC3 EVI2B FAM209A FKBP7 GPX8 HTR2B LMNA LRRC59 MFF MUC1 PLEKHF2 PLEKHO1 PLPP2 SAR1A TMED8 TMEM52B TMEM79 TMX2
Entrez ID		83692	133022
HPRD ID		06469	11643
Ensembl ID		ENSG00000102181	ENSG00000174599
Uniprot IDs		A0A024RC16 Q8TCZ2	Q8N609
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Response To Endoplasmic Reticulum Stress TRC Complex Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Response To Endoplasmic Reticulum Stress Zinc:proton Antiporter Activity Regulation Of Cellular Response To Stress Zinc Ion Import Into Organelle Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Monoatomic Cation Transmembrane Transporter Activity Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Zinc Ion Transport Protein Insertion Into ER Membrane Protein Targeting To ER Regulation Of Intrinsic Apoptotic Signaling Pathway Intracellular Zinc Ion Homeostasis Positive Regulation Of Proteolysis Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Protein Catabolic Process Establishment Of Protein Localization To Membrane Positive Regulation Of Protein Catabolic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Calcium Ion Transmembrane Transport Polyubiquitin Modification-dependent Protein Binding Membrane Response To Zinc Ion Transport Vesicle Membrane Negative Regulation Of Calcium Ion Transport Autophagy Endoplasmic Reticulum Unfolded Protein Response Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Negative Regulation Of Store-operated Calcium Channel Activity Protein Insertion Into Membrane Protein Targeting To Membrane Cellular Response To Stress Negative Regulation Of Cation Transmembrane Transport Cytoplasmic Vesicle Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Protein Catabolic Process Autophagosome	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane
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