TRAM1L1 and PLPP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRAM1L1	PLPP2
Description		translocation associated membrane protein 1 like 1	phospholipid phosphatase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Caveola Membrane Early Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Phosphatidate Phosphatase Activity Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Protein Transport Protein Insertion Into ER Membrane	Lipid Metabolic Process Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Signal Transduction Sphingolipid Catabolic Process Phospholipid Dephosphorylation
Pathways			Sphingolipid catabolism
Drugs
Diseases
GWAS		Bipolar disorder ( 33169155) Bronchopulmonary dysplasia ( 23897914) Lateral ventricle volume in trauma-exposed individuals ( 29187748) Metabolite levels ( 23823483) Obesity (extreme) ( 19553259) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		29 interacting genes: ASGR2 BDKRB1 BSCL2 CD53 CD79A CD99L2 CLEC1A CLSTN3 CREB3 CREB3L1 CYBC1 ERGIC3 EVI2B FAM209A FKBP7 GPX8 HTR2B LMNA LRRC59 MFF MUC1 PLEKHF2 PLEKHO1 PLPP2 SAR1A TMED8 TMEM52B TMEM79 TMX2	9 interacting genes: BAG6 HNF4A JAGN1 MRPL44 NOTCH2NLA NSG1 TRAM1L1 UNC119 VSTM1
Entrez ID		133022	8612
HPRD ID		11643	06180
Ensembl ID		ENSG00000174599	ENSG00000141934
Uniprot IDs		Q8N609	O43688
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane
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