AKAP17A and HMGXB4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AKAP17A	HMGXB4
Description		A-kinase anchoring protein 17A	HMG-box containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol Nuclear Speck	Nucleus NURF Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Protein Kinase A Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription MRNA Processing Signal Transduction RNA Splicing B Cell Activation Regulation Of RNA Splicing	Endosome To Lysosome Transport Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 25673412 34021172) Hip index ( 34021172) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		19 interacting genes: ANKRD36B CCDC85B CEP70 CSNK1E DVL3 HMGXB4 KRT40 MDFI NINL RNF4 SDCBP2 SRRM4 SRSF1 THAP1 TRAF1 TTC3 UBE2I UFL1 ZRANB2	27 interacting genes: AKAP17A CACNA1I CREBBP DNAL4 EPM2A H3-4 HABP4 INO80B JMJD6 LENG8 MX1 NKAPD1 NR1H2 PIAS2 SRPK2 STAC3 STRBP SUMO2 TAB1 TENT5B TNNT1 TSC22D1 TSPYL2 UBE2I UBL5 UROD ZCCHC10
Entrez ID		8227	10042
HPRD ID		02419	05267
Ensembl ID		ENSG00000197976	ENSG00000100281
Uniprot IDs		Q02040 Q05DA9	Q7Z641 Q9UGU5
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding	SUMO Transferase Activity Protein Sumoylation Protein Tag Activity Regulation Of RNA Splicing RNA Splicing MRNA Metabolic Process Nuclear Body Organization Nucleus Chromatin Remodeling Nucleic Acid Metabolic Process PML Body MRNA Processing Voltage-gated Calcium Channel Complex Nucleoplasm Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Binding Presynaptic Cytosol Postsynaptic Cytosol RNA Metabolic Process Slow-twitch Skeletal Muscle Fiber Contraction Skeletal Muscle Contraction SUMO Conjugating Enzyme Activity Positive Regulation Of Secretion Of Lysosomal Enzymes Uroporphyrinogen Decarboxylase Activity Carbohydrate Phosphatase Activity Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Chromatin Organization
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