ESS2 and DHX16

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		ESS2	DHX16
Description		ess-2 spliceosome associated protein	DEAH-box helicase 16
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U2-type Precatalytic Spliceosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA Hydrolase Activity ATP Hydrolysis Activity Pattern Recognition Receptor Activity Ubiquitin Binding Molecular Adaptor Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing	MRNA Splicing, Via Spliceosome Immune System Process MRNA Processing RNA Splicing Innate Immune Response Antiviral Innate Immune Response
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		33 interacting genes: ARMC7 CCDC57 CDK5RAP3 CEP55 CPSF7 CRP DGCR6 DHX16 EHMT2 EXOC8 EXOSC7 HOOK1 ITCH KRT31 LYST NEDD4 OGT OIP5 PFDN1 PRPF38B PRRC2B QARS1 RACK1 RBM22 RBM4 SMARCD1 THOC1 TRAK1 TTC14 UTP6 VIM WNK2 YAP1	13 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 MYO19 RIGI RNF10 SNRNP27 TFIP11 XAB2
Entrez ID		8220	8449
HPRD ID		03452	04555
Ensembl ID		ENSG00000100056	ENSG00000204560
Uniprot IDs		F8WEF8 Q96DF8	A0A1U9X7L7 B4DZ28 O60231 Q5SQH4 Q5SQH5
PDB IDs		8C6J 8RO2 9FMD	5Z56 5Z57 5Z58 6FF7 7DVQ 7QTT 8CH6 8I0R 8I0S 8I0T 8I0U 8I0V
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Cyclin Binding RNA Processing MRNA Metabolic Process MRNA Processing RNA Splicing Lysosomal Transport Positive Regulation Of Stem Cell Population Maintenance Endosome To Lysosome Transport Vacuolar Transport Negative Regulation Of MAPK Cascade RNA Binding Regulation Of Stem Cell Population Maintenance Spliceosomal Complex Molecular Adaptor Activity Proline-rich Region Binding Regulation Of Macroautophagy Pre-mRNA Binding	MRNA Metabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Catalytic Step 2 Spliceosome RNA Splicing MRNA Processing RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Mitochondrion Migration Along Actin Filament
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