FBXO38 and SOX30

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		FBXO38	SOX30
Description		F-box protein 38	SRY-box transcription factor 30
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Chromocenter
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Adaptive Immune Response Immune System Process Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Neuron Projection Development Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of T Cell Activation Positive Regulation Of T Cell Activation Protein K48-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II Proacrosomal Vesicle Fusion
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 33909500) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Lung function (FEV1/FVC) ( 31453325) Lung function (FEV1/FVC) variance ( 31453325) Mean reticulocyte volume ( 32888494) Periodontal microbiota ( 22699663) Zinc levels ( 26025379)	Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)
Interacting Genes		9 interacting genes: ABL2 APP CREBBP KLF7 PPM1G RING1 SOX30 SUMO2 USP7	19 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FHL2 FLI1 GNAI3 GP2 KIFC3 MRPS5 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		81545	11063
HPRD ID		09775	09461
Ensembl ID		ENSG00000145868	ENSG00000039600
Uniprot IDs		Q6AZE0 Q6PIJ6	B4DXW7 O94993
PDB IDs			7JJK
Enriched GO Terms of Interacting Partners?		Protein Modification Process Positive Regulation Of T Cell Migration Positive Regulation Of Lymphocyte Migration Regulation Of Lymphocyte Migration Regulation Of T Cell Migration Negative Regulation Of Cell Communication Protein Metabolic Process Negative Regulation Of Signaling Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of RNA Metabolic Process Chromatin Remodeling Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Post-translational Protein Modification P53 Binding Positive Regulation Of RNA Biosynthetic Process Regulation Of Protein Catabolic Process Regulation Of Protein Localization Positive Regulation Of DNA-templated Transcription Nuclear Body Nucleoplasm Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Negative Regulation Of Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Lipoprotein Particle Positive Regulation Of Protein Import Histone H3K27 Acetyltransferase Activity Proacrosomal Vesicle Fusion Positive Regulation Of Mononuclear Cell Migration Regulation Of Metabolic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of RNA Metabolic Process
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