SOX30 and DDX56

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SOX30	DDX56
Description		SRY-box transcription factor 30	DEAD-box helicase 56
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Chromocenter	Nucleus Nucleolus Cytosol Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity RNA Stem-loop Binding Protein Sequestering Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II Proacrosomal Vesicle Fusion	Cytoplasmic Pattern Recognition Receptor Signaling Pathway RRNA Processing Protein Import Into Nucleus Positive Regulation Of Neuron Projection Development Negative Regulation Of Type I Interferon Production Ribosome Biogenesis Host-mediated Perturbation Of Viral RNA Genome Replication Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)	LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		19 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FHL2 FLI1 GNAI3 GP2 KIFC3 MRPS5 NME1 NUDT3 PAXIP1 TRAF2	6 interacting genes: EHD2 EIF4A3 OGT SOX30 USP33 ZNF408
Entrez ID		11063	54606
HPRD ID		09461	12154
Ensembl ID		ENSG00000039600	ENSG00000136271
Uniprot IDs		B4DXW7 O94993	Q9NY93
PDB IDs		7JJK
Enriched GO Terms of Interacting Partners?			Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Negative Regulation Of Translation Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Translation Protein O-acetylglucosaminyltransferase Activity Selenocysteine Insertion Sequence Binding Negative Regulation Of Translational Elongation Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Translation At Postsynapse Proacrosomal Vesicle Fusion VCB Complex
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