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CCDC33 and RAD51D
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
CCDC33
RAD51D
Description
coiled-coil domain containing 33
RAD51 paralog D
Image
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Chromosome
Cytoplasm
Centrosome
Microtubule Organizing Center
Cytoskeleton
Rad51B-Rad51C-Rad51D-XRCC2 Complex
Molecular Function
Protein Binding
Nucleotide Binding
Four-way Junction DNA Binding
DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
ATP-dependent Activity, Acting On DNA
Gamma-tubulin Binding
ATP-dependent DNA Damage Sensor Activity
Biological Process
Telomere Maintenance Via Recombination
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Repair
DNA Recombination
DNA Damage Response
Reciprocal Meiotic Recombination
Interstrand Cross-link Repair
DNA Strand Invasion
Chromosome Organization
Regulation Of Cell Cycle
Pathways
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
TP53 Regulates Transcription of DNA Repair Genes
Defective homologous recombination repair (HRR) due to BRCA1 loss of function
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Impaired BRCA2 binding to PALB2
Drugs
Diseases
GWAS
Bacterial meningitis (
31092817
)
Coffee consumption (cups per day) (
31837886
)
Craniofacial microsomia (
26853712
)
Diastolic blood pressure (
30224653
)
Diisocyanate-induced asthma (
25918132
)
Hip circumference adjusted for BMI (
34021172
)
Obesity-related traits (
23251661
)
Systolic blood pressure (
30578418
)
Interacting Genes
160 interacting genes:
ABCF3
ABLIM3
AIRIM
ANKS1A
AP1M1
APP
ARHGEF6
ARIH2
ARMC7
ARNT2
ATOSB
BCCIP
BLK
BLZF1
BYSL
CABP2
CALCOCO2
CCDC102B
CCDC57
CCDC6
CCDC85B
CCHCR1
CCNH
CDC23
CDCA7L
CDKN2B
CENPP
CFAP206
CHCHD3
CINP
CIRSR
CRYBA2
CRYBA4
CTNNA3
DGCR6
DIP2A
DVL2
DVL3
EAF1
EFEMP2
EHMT2
EMC2
EMD
ESRRG
EXOC8
FAM124A
FAM161A
FRS3
FXR2
GCC1
GPANK1
GPATCH2L
GRN
GYS1
HEXIM2
HGS
HNRNPF
HNRNPK
HOOK2
HOXA1
HSF2BP
IL16
ING5
ITGB1BP1
KANK2
KCTD19
KCTD9
KDM1A
KHDRBS3
KIFC3
KLHL38
KXD1
L3MBTL2
LDOC1
LMO1
LMO2
LMO3
LNX1
MAGED1
MAGOHB
MAPK9
MDFI
MFAP1
MID2
MIPOL1
MISP
MKRN3
MLH1
MOS
NAB2
NCK2
NDOR1
NECAB2
NEFL
NINL
NME7
OSGIN1
OSTF1
PCSK5
PID1
PIK3R3
PIN1
PLA2G6
PLSCR1
PNMA1
PNMA2
POLR1C
PPP2R3C
PRKAA2
PRKAB2
PRPF31
PTGER3
PTK6
QARS1
RAD51D
RAD54B
RBMX
RHOXF2
RNF6
SCNM1
SMAD3
SMARCB1
SMARCD1
SMYD1
SPAG5
SPG21
STK16
STX11
SYT17
TASOR2
TCEANC
TGFB1
TMCC2
TNS2
TRAF2
TRIM23
TRIM37
TRIM42
TRIM59
TSC22D4
TSEN15
TSGA10
TTC19
TUFT1
TXK
TXLNA
UBASH3A
UBQLN4
UNG
USHBP1
VPS52
WT1
YES1
ZBTB8A
ZGPAT
ZNF330
ZNF572
ZNF688
ZNF76
ZNRD2
49 interacting genes:
AMOTL2
BLM
C1orf94
CCDC33
CCNL1
CEP57L1
EFHC2
GEMIN4
HSF2BP
IHO1
IKZF1
IKZF3
KATNBL1
KIFC3
KRT15
LIMS1
LNX1
LZTS2
MAPK8IP3
MEOX2
NFKBID
PICK1
PNMA1
POLDIP3
PRDM14
PRDM6
RAD51B
RAD51C
RBM48
REL
RHOU
RNF138
SORBS3
SPATC1L
STX11
SWSAP1
TCF4
TEPSIN
TLE5
TRIM14
TTC23
VPS9D1
XRCC2
XRCC3
ZBTB42
ZC2HC1C
ZNF343
ZNF774
ZSWIM7
Entrez ID
80125
5892
HPRD ID
09959
04261
Ensembl ID
ENSG00000140481
ENSG00000185379
Uniprot IDs
A0A1B0GV97
Q8N5R6
O75771
PDB IDs
2KZ3
8FAZ
8GBJ
8OUY
8OUZ
Enriched GO Terms of Interacting Partners
?
Protein Binding
Identical Protein Binding
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Nucleoplasm
Cytoplasm
Non-membrane Spanning Protein Tyrosine Kinase Activity
Regulation Of Macromolecule Biosynthetic Process
CD4 Receptor Binding
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Regulation Of Primary Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Neuron Maturation
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Speck
Spliceosomal Complex
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Enzyme Binding
Four-way Junction DNA Binding
Recombinational Repair
Double-strand Break Repair Via Homologous Recombination
Double-strand Break Repair
Replication Fork
DNA Recombination
Rad51B-Rad51C-Rad51D-XRCC2 Complex
ATP-dependent DNA Damage Sensor Activity
Protein Binding
Rad51C-XRCC3 Complex
Shu Complex
DNA Repair
DNA Metabolic Process
DNA Binding
Resolution Of DNA Recombination Intermediates
Single-stranded DNA Binding
Crossover Junction DNA Endonuclease Activity
DNA Damage Response
Telomeric Loop Disassembly
T-circle Formation
Telomere Maintenance Via Recombination
Zinc Ion Binding
Somite Development
Meiosis I Cell Cycle Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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