UBTD1 and BCOR

Number of citations of the paper that reports this interaction (PubMedID 24211586)
0

Data Source:
BioGRID (two hybrid)

		UBTD1	BCOR
Description		ubiquitin domain containing 1	BCL6 corepressor
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm BCOR Complex
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Heat Shock Protein Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Hatching Chromatin Organization Chromatin Remodeling Heart Development Negative Regulation Of Bone Mineralization Odontogenesis Negative Regulation Of DNA-templated Transcription Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization
Pathways
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS		Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio ( 26634245)	Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Refractive error ( 32231278) Venous thromboembolism ( 31676865)
Interacting Genes		20 interacting genes: BCOR BRD10 CD1A FZD5 MID1 MID2 MRFAP1 MRFAP1L1 PFKM RANBP2 RNF10 RNF5 TEAD1 TP53BP2 TRAF6 TRIM39 TRIM50 UBE2D1 UBE2D4 WWP2	16 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 SP1 UBTD1 USP7 ZBTB5
Entrez ID		80019	54880
HPRD ID		08568	06458
Ensembl ID		ENSG00000165886	ENSG00000183337
Uniprot IDs		Q9HAC8	H7BZ37 H7C231 Q6W2J9
PDB IDs			2N1L 3BIM 4HPL 6B7G 8HCU
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Transferase Activity Post-translational Protein Modification Protein Ubiquitination Ubiquitin-protein Transferase Activity Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Modification Process Positive Regulation Of T Cell Mediated Immunity Identical Protein Binding Protein Autoubiquitination Protein Localization To Microtubule Regulation Of T Cell Mediated Immunity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Positive Regulation Of T Cell Cytokine Production Ubiquitin Conjugating Enzyme Activity Zinc Ion Binding Phosphoprotein Binding Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of T Cell Cytokine Production Phosphofructokinase Activity Glycolysis From Storage Polysaccharide Through Glucose-1-phosphate Negative Regulation Of Tooth Mineralization BCOR Complex Antigen Processing And Presentation Of Exogenous Antigen Regulation Of Lymphocyte Mediated Immunity Protein Localization To Cytoskeleton Toll-like Receptor Signaling Pathway Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Adaptive Immune Response Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Proteasomal Protein Catabolic Process Positive Regulation Of Transcription By RNA Polymerase II Cytoplasmic Periphery Of The Nuclear Pore Complex	Histone Deacetylase Activity, Hydrolytic Mechanism Protein Lysine Deacetylase Activity Histone Deacetylase Activity Histone Deacetylase Binding Negative Regulation Of Gene Expression, Epigenetic Histone Deacetylase Complex Protein Deacetylation Transcription Corepressor Binding Negative Regulation Of Myotube Differentiation Epigenetic Regulation Of Gene Expression Macromolecule Deacylation Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Myotube Differentiation Chromatin Organization Transcription Repressor Complex DNA-binding Transcription Factor Binding Negative Regulation Of Muscle Cell Differentiation Chromatin Remodeling Regulation Of Striated Muscle Cell Differentiation Protein Lysine Delactylase Activity Negative Regulation Of Gene Expression NF-kappaB Binding Negative Regulation Of Macromolecule Biosynthetic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Muscle Cell Differentiation Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of RNA Metabolic Process Calcium-dependent Phospholipid Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Differentiation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Deacetylase Activity Cellular Response To Parathyroid Hormone Stimulus Cellular Response To Calcium Ion Nucleus Chromatin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Rhythmic Process Transcription Cis-regulatory Region Binding
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