BCOR

Description		BCL6 corepressor
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm BCOR Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Heat Shock Protein Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Hatching Chromatin Organization Chromatin Remodeling Heart Development Negative Regulation Of Bone Mineralization Odontogenesis Negative Regulation Of DNA-templated Transcription Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Refractive error ( 32231278) Venous thromboembolism ( 31676865)
Novel Interacting Genes		16 novel interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 SP1 UBTD1 USP7 ZBTB5
Interacting Genes		16 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 SP1 UBTD1 USP7 ZBTB5
Entrez ID		54880
HPRD ID		06458
Ensembl ID		ENSG00000183337
Uniprot IDs		H7BZ37 H7C231 Q6W2J9
PDB IDs		2N1L 3BIM 4HPL 6B7G 8HCU
Enriched GO Terms of Interacting Partners?		Histone Deacetylase Activity, Hydrolytic Mechanism Protein Lysine Deacetylase Activity Histone Deacetylase Activity Histone Deacetylase Binding Negative Regulation Of Gene Expression, Epigenetic Histone Deacetylase Complex Protein Deacetylation Transcription Corepressor Binding Negative Regulation Of Myotube Differentiation Epigenetic Regulation Of Gene Expression Macromolecule Deacylation Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Myotube Differentiation Chromatin Organization Transcription Repressor Complex DNA-binding Transcription Factor Binding Negative Regulation Of Muscle Cell Differentiation Chromatin Remodeling Regulation Of Striated Muscle Cell Differentiation Protein Lysine Delactylase Activity Negative Regulation Of Gene Expression NF-kappaB Binding Negative Regulation Of Macromolecule Biosynthetic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Muscle Cell Differentiation Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of RNA Metabolic Process Calcium-dependent Phospholipid Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Differentiation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Deacetylase Activity Cellular Response To Parathyroid Hormone Stimulus Cellular Response To Calcium Ion Nucleus Chromatin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Rhythmic Process Transcription Cis-regulatory Region Binding
Tagcloud ?