ARSJ and ZMIZ2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ARSJ	ZMIZ2
Description		arylsulfatase family member J	zinc finger MIZ-type containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen Actin Cytoskeleton	Chromatin Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork
	Molecular Function	Arylsulfatase Activity Sulfuric Ester Hydrolase Activity Hydrolase Activity Metal Ion Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding SUMO Ligase Activity
	Biological Process		Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II SMAD Protein Signal Transduction
Pathways		The activation of arylsulfatases Glycosphingolipid catabolism
Drugs
Diseases
GWAS		Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Blood pressure measurement (high sodium intervention) ( 24165912) Impulsivity (motor) ( 30718321)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Fasting glucose ( 34059833) General cognitive ability ( 29844566) Hematocrit ( 32888494) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		4 interacting genes: KRT31 TRAF1 TRAF2 ZMIZ2	27 interacting genes: AKAP19 AR ARSJ ASB13 BANP CPNE7 CRCP FRS3 GCM2 INTS4 KPNA4 LRRC37A11P MCPH1 MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELENOV SOCS6 SS18L1 SSX2 SUMO2 TP53 TRAPPC6A
Entrez ID		79642	83637
HPRD ID		08034	13225
Ensembl ID		ENSG00000180801	ENSG00000122515
Uniprot IDs		Q5FYB0	E7EWM3 Q8NF64
PDB IDs
Enriched GO Terms of Interacting Partners?		Thioesterase Binding Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor-mediated Signaling Pathway Signaling Adaptor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of DNA-binding Transcription Factor Activity TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex CD27 Signaling Pathway Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Ubiquitin Protein Ligase Binding Regulation Of Canonical NF-kappaB Signal Transduction CD40 Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Interleukin-17-mediated Signaling Pathway CD40 Receptor Complex Positive Regulation Of JUN Kinase Activity Regulation Of Apoptotic Signaling Pathway SUMO Ligase Activity Cytokine-mediated Signaling Pathway TORC2 Signaling Cellular Response To Nitric Oxide Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding Cellular Response To Reactive Nitrogen Species Response To Nitric Oxide Nuclear Replication Fork Programmed Necrotic Cell Death Zinc Ion Binding Cell Surface Receptor Signaling Pathway SMAD Protein Signal Transduction Positive Regulation Of T Cell Cytokine Production	Postsynaptic Cytosol
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