FAM118B and RASGRP2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		FAM118B	RASGRP2
Description		family with sequence similarity 118 member B	RAS guanyl releasing protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cajal Body	Cytoplasm Cytosol Plasma Membrane Membrane Ruffle Membrane Cell Projection Neuron Projection Synapse
	Molecular Function	Protein Binding Identical Protein Binding	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Zinc Ion Binding Lipid Binding Diacylglycerol Binding GTPase Regulator Activity Metal Ion Binding
	Biological Process		Regulation Of Cell Growth Signal Transduction Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction Positive Regulation Of GTPase Activity Cellular Response To Calcium Ion
Pathways			Effects of PIP2 hydrolysis FCERI mediated NF-kB activation Integrin signaling Rap1 signalling
Drugs
Diseases
GWAS			Urate levels ( 21768215)
Interacting Genes		29 interacting genes: BAG5 CEP126 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 MCM3AP MED31 NGEF PDCD10 PIAS2 QARS1 RAD54L2 RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746	9 interacting genes: APP CEBPA DAPK1 DISP3 FAM118B KRAS NRAS RAP1A SNCA
Entrez ID		79607	10235
HPRD ID		07952	09278
Ensembl ID		ENSG00000197798	ENSG00000068831
Uniprot IDs		J3KP39 Q9BPY3	B3KV60 Q7LDG7
PDB IDs			2MA2 6AXF
Enriched GO Terms of Interacting Partners?		Protein Sumoylation PML Body Organization	Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity GDP Binding G Protein Activity Protein-containing Complex Binding Liver Development GTP Binding Intracellular Signaling Cassette Regulation Of Presynapse Organization Intracellular Signal Transduction Positive Regulation Of Inflammatory Response Modulation Of Chemical Synaptic Transmission Positive Regulation Of Endocytosis Regulation Of Presynapse Assembly Regulation Of Neurotransmitter Uptake Cellular Response To Metal Ion Cellular Response To Copper Ion Identical Protein Binding Amyloid Fibril Formation Positive Regulation Of Catabolic Process Regulation Of Synaptic Plasticity Response To Peptide Response To Cytokine Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Synaptic Vesicle Exocytosis Response To Copper Ion Cell Surface Receptor Signaling Pathway Negative Regulation Of Exocytosis Presynapse Cellular Response To Nerve Growth Factor Stimulus Homeostatic Process Response To Nerve Growth Factor Regulation Of Neuron Apoptotic Process Amyloid-beta Complex Positive Regulation Of Metabolic Process Regulation Of Cell Junction Assembly Positive Regulation Of Phosphate Metabolic Process Growth Cone Lamellipodium Cognition Visual Behavior Regulation Of Response To Calcium Ion Learning Or Memory Macrophage Activation Response To Growth Factor Amylin Binding Regulation Of Protein Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Visual Learning
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