RASGRP2

Description		RAS guanyl releasing protein 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Ruffle Membrane Cell Projection Neuron Projection Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Zinc Ion Binding Lipid Binding Diacylglycerol Binding GTPase Regulator Activity Metal Ion Binding
	Biological Process	Regulation Of Cell Growth Signal Transduction Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction Positive Regulation Of GTPase Activity Cellular Response To Calcium Ion
Pathways		Effects of PIP2 hydrolysis FCERI mediated NF-kB activation Integrin signaling Rap1 signalling
Drugs
Diseases
GWAS		Urate levels ( 21768215)
Novel Interacting Genes		9 novel interacting genes: APP CEBPA DAPK1 DISP3 FAM118B KRAS NRAS RAP1A SNCA
Interacting Genes		9 interacting genes: APP CEBPA DAPK1 DISP3 FAM118B KRAS NRAS RAP1A SNCA
Entrez ID		10235
HPRD ID		09278
Ensembl ID		ENSG00000068831
Uniprot IDs		B3KV60 Q7LDG7
PDB IDs		2MA2 6AXF
Enriched GO Terms of Interacting Partners?		Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity GDP Binding G Protein Activity Protein-containing Complex Binding Liver Development GTP Binding Intracellular Signaling Cassette Regulation Of Presynapse Organization Intracellular Signal Transduction Positive Regulation Of Inflammatory Response Modulation Of Chemical Synaptic Transmission Positive Regulation Of Endocytosis Regulation Of Presynapse Assembly Regulation Of Neurotransmitter Uptake Cellular Response To Metal Ion Cellular Response To Copper Ion Identical Protein Binding Amyloid Fibril Formation Positive Regulation Of Catabolic Process Regulation Of Synaptic Plasticity Response To Peptide Response To Cytokine Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Synaptic Vesicle Exocytosis Response To Copper Ion Cell Surface Receptor Signaling Pathway Negative Regulation Of Exocytosis Presynapse Cellular Response To Nerve Growth Factor Stimulus Homeostatic Process Response To Nerve Growth Factor Regulation Of Neuron Apoptotic Process Amyloid-beta Complex Positive Regulation Of Metabolic Process Regulation Of Cell Junction Assembly Positive Regulation Of Phosphate Metabolic Process Growth Cone Lamellipodium Cognition Visual Behavior Regulation Of Response To Calcium Ion Learning Or Memory Macrophage Activation Response To Growth Factor Amylin Binding Regulation Of Protein Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Visual Learning
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