TGM3 and CALML5

Number of citations of the paper that reports this interaction (PubMedID 10777582)
0

Data Source:
HPRD (in vitro)

		TGM3	CALML5
Description		transglutaminase 3	calmodulin like 5
Image
GO Annotations	Cellular Component	Cytoplasm Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Extracellular Exosome	Extracellular Region Cytoplasm Ficolin-1-rich Granule Lumen
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Catalytic Activity Structural Molecule Activity Calcium Ion Binding Protein Binding Transferase Activity Acyltransferase Activity Metal Ion Binding	Calcium Ion Binding Protein Binding Enzyme Regulator Activity Metal Ion Binding
	Biological Process	Peptide Cross-linking Keratinocyte Differentiation Hair Follicle Morphogenesis Keratinization Protein Modification Process	Microtubule Cytoskeleton Organization Signal Transduction Epidermis Development
Pathways			Neutrophil degranulation Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs		5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Monophosphate B-2-Octylglucoside Guanosine-5'-Diphosphate
Diseases
GWAS		Basal cell carcinoma ( 24403052 25855136 27539887 31174203 33549134) Inflammatory skin disease ( 25574825) Keratinocyte cancer (MTAG) ( 31174203) Metabolite levels ( 23823483) Non-melanoma skin cancer ( 29739929)
Interacting Genes		4 interacting genes: CALML5 HLCS HMGB1 UCHL5	4 interacting genes: CDC42 TGM3 WEE2-AS1 WT1
Entrez ID		7053	51806
HPRD ID		02584	05538
Ensembl ID		ENSG00000125780	ENSG00000178372
Uniprot IDs		Q08188	Q53H37 Q9NZT1
PDB IDs		1L9M 1L9N 1NUD 1NUF 1NUG 8OXV 8OXW 8OXX 8OXY 8RMX 8RMY	2B1U
Enriched GO Terms of Interacting Partners?		Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Biotin Metabolic Process Biotin Binding Response To Biotin Regulation Of Mismatch Repair Negative Regulation Of DNA-templated Transcription Initiation C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex Positive Regulation Of Hematopoietic Progenitor Cell Differentiation Calcium-dependent Protein Kinase Regulator Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway T-helper 1 Cell Activation Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of DNA Repair Positive Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Myeloid Progenitor Cell Differentiation Ficolin-1-rich Granule Lumen DNA Recombination Negative Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Positive Regulation Of DNA Metabolic Process Supercoiled DNA Binding Regulation Of DNA Repair Positive Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Dendritic Cell Differentiation Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Apoptotic Cell Clearance Neutrophil Clearance DNA Geometric Change Regulation Of Glycogen Catabolic Process Bubble DNA Binding Forebrain Morphogenesis Regulation Of Apoptotic Cell Clearance Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Chromosome Organization Regulation Of Toll-like Receptor 9 Signaling Pathway DNA Topological Change Endothelial Cell Chemotaxis Nuclear Lamina RAGE Receptor Binding Regulation Of T Cell Mediated Immune Response To Tumor Cell T-helper 1 Cell Differentiation DNA Binding, Bending Cellular Response To Interleukin-7 Response To Interleukin-7 Positive Regulation Of Monocyte Chemotactic Protein-1 Production	Positive Regulation Of Pinocytosis Apolipoprotein A-I Receptor Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Endothelin Receptor Signaling Pathway Involved In Heart Process Epithelium Development Tube Development Positive Regulation Of Growth Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Establishment Of Golgi Localization Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Epithelial Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Protein-glutamine Gamma-glutamyltransferase Activity Hemi-methylated DNA-binding Diaphragm Development Negative Regulation Of Cell Proliferation Involved In Kidney Development Negative Regulation Of Female Gonad Development Regulation Of Female Gonad Development Thorax And Anterior Abdomen Determination Positive Regulation Of Male Gonad Development Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Negative Regulation Of Glomerular Mesangial Cell Proliferation Adrenal Cortex Formation S-shaped Body Morphogenesis Positive Regulation Of Metanephric Ureteric Bud Development Cardiac Muscle Cell Fate Commitment Double-stranded Methylated DNA Binding Metanephric Mesenchyme Development Metanephric S-shaped Body Morphogenesis Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Pre-mRNA 5'-splice Site Binding MRNA 5'-splice Site Recognition Leading Edge Membrane Thioesterase Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Neuron Fate Determination Anatomical Structure Morphogenesis Golgi Transport Complex Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Nephron Tubule Morphogenesis Podocyte Differentiation Glomerular Basement Membrane Development Regulation Of Glomerular Mesangial Cell Proliferation Regulation Of Cell Growth Golgi Localization
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