DYNLT3 and CD5

Number of citations of the paper that reports this interaction (PubMedID 9692886)
0

Data Source:
HPRD (two hybrid)

		DYNLT3	CD5
Description		dynein light chain Tctex-type 3	CD5 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Chromosome Cytoplasm Cytoskeleton Cytoplasmic Dynein Complex Microtubule Dynein Complex Mitotic Spindle Astral Microtubule	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Microtubule-based Movement Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Cell Division	Cell Recognition T Cell Costimulation Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Coffee consumption ( 31046077) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088 24076602) Rheumatoid arthritis ( 23143596 24390342 30423114) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		15 interacting genes: C2orf15 CCL28 CD5 CYBB DYNC1I1 DYNC1I2 FOS IFITM1 NIF3L1 PMS1 PVR TESC UIMC1 VDAC1 ZC3H14	27 interacting genes: CAMK2D CAPN1 CBL CD2 CD247 CD4 CD6 CD72 CD79A CD79B CFL1 CSNK2A1 CTTN DNASE1L2 DYNLT3 FYN HNRNPU LCK MX1 PIK3R1 PRKCA PRKCB PRKCG PTPN6 RASA1 ZAP70 ZNHIT2
Entrez ID		6990	921
HPRD ID		02249	01078
Ensembl ID		ENSG00000165169	ENSG00000110448
Uniprot IDs		P51808	P06127
PDB IDs			2JA4 2JOP 2JP0 2OTT
Enriched GO Terms of Interacting Partners?		Dynein Light Chain Binding Dynein Heavy Chain Binding Cytoplasmic Dynein Complex	Cell Surface Receptor Signaling Pathway Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Phosphotyrosine Residue Binding Plasma Membrane Leukocyte Activation Signal Transduction Positive Regulation Of Immune System Process Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Activation Adaptive Immune Response Regulation Of Immune System Process T Cell Receptor Complex B Cell Receptor Signaling Pathway Cell-cell Junction Immune Response-activating Signaling Pathway Immune Response Regulation Of Immune Response Signaling Receptor Binding Immune System Process Immune Response-regulating Signaling Pathway Activation Of Immune Response Regulation Of Cell Adhesion Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Immune Response Regulation Of Apoptotic Process Protein Kinase Activity Identical Protein Binding T Cell Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Programmed Cell Death Protein Phosphorylation Intracellular Signal Transduction Membrane Raft Peptidyl-tyrosine Phosphorylation Phosphorylation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Lymphocyte Differentiation Phosphatidylinositol 3-kinase Binding Histone H3T6 Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of T Cell Activation Kinase Activity Regulation Of Hemopoiesis Negative Regulation Of Apoptotic Process Positive Regulation Of Leukocyte Cell-cell Adhesion
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