SSR2 and SRPRA

Number of citations of the paper that reports this interaction (PubMedID 3021779)
30

Data Source:
HPRD (in vitro, in vivo)

		SSR2	SRPRA
Description		signal sequence receptor subunit 2	SRP receptor subunit alpha
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding RNA Binding GTPase Activity Signal Recognition Particle Binding Protein Binding GTP Binding
	Biological Process	In Utero Embryonic Development Cotranslational Protein Targeting To Membrane	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Intracellular Protein Transport Protein Targeting To ER
Pathways		SRP-dependent cotranslational protein targeting to membrane	SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		1 interacting genes: SRPRA	3 interacting genes: RPL10A RUSC2 SSR2
Entrez ID		6746	6734
HPRD ID		02923	01645
Ensembl ID		ENSG00000163479	ENSG00000182934
Uniprot IDs		P43308	P08240
PDB IDs		8B6L	2FH5 2GO5 5L3Q 6Y32 7NFX
Enriched GO Terms of Interacting Partners?		Signal Recognition Particle Binding SRP-dependent Cotranslational Protein Targeting To Membrane Signal Recognition Particle Receptor Complex SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Protein Targeting Establishment Of Protein Localization To Membrane
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