SRPRA and RUSC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		SRPRA	RUSC2
Description		SRP receptor subunit alpha	RUN and SH3 domain containing 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Nucleotide Binding RNA Binding GTPase Activity Signal Recognition Particle Binding Protein Binding GTP Binding	Protein Binding Small GTPase Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Intracellular Protein Transport Protein Targeting To ER
Pathways		SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS			Psoriasis ( 25903422)
Interacting Genes		3 interacting genes: RPL10A RUSC2 SSR2	12 interacting genes: DLST EGFR FXR1 GIT2 GOLGA2 KHDRBS1 KLC2 MAGEC1 RAB1A RAB1B SIGMAR1 SRPRA
Entrez ID		6734	9853
HPRD ID		01645	18009
Ensembl ID		ENSG00000182934	ENSG00000198853
Uniprot IDs		P08240	Q8N2Y8
PDB IDs		2FH5 2GO5 5L3Q 6Y32 7NFX	6IF2
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Metabolic Process Virion Assembly Cadherin Binding Establishment Of Endothelial Intestinal Barrier Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Regulation Of Protein Metabolic Process Establishment Of Endothelial Barrier Endothelial Cell Development Dihydrolipoyllysine-residue Succinyltransferase Activity Multivesicular Body, Internal Vesicle Lumen Grb2-Sos Complex Kinesin I Complex Golgi Membrane Golgi Vesicle Transport Establishment Of Protein Localization Organelle Assembly G Protein Activity GTPase Activity Shc-EGFR Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Oxoadipate Dehydrogenase Complex Positive Regulation Of Protein Kinase C Signaling Negative Regulation Of Catabolic Process Epidermal Growth Factor Receptor Activity Autophagosome Assembly GTP Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Autophagosome Organization L-lysine Catabolic Process Membrane Epidermal Growth Factor Binding Positive Regulation Of Protein Glycosylation Establishment Of Localization In Cell Signal Recognition Particle Receptor Complex
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