SSR1 and DKC1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SSR1	DKC1
Description		signal sequence receptor subunit 1	dyskerin pseudouridine synthase 1
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Fibrillar Center Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cytoplasm Cajal Body Box H/ACA SnoRNP Complex Box H/ACA ScaRNP Complex Box H/ACA Telomerase RNP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Telomerase Activity RNA Binding Protein Binding Pseudouridine Synthase Activity Isomerase Activity Box H/ACA SnoRNA Binding Telomerase RNA Binding
	Biological Process	Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Population Proliferation	Enzyme-directed RRNA Pseudouridine Synthesis Box H/ACA Sno(s)RNA 3'-end Processing Pseudouridine Synthesis RRNA Processing RNA Processing Telomere Maintenance Via Telomerase RNA Modification RRNA Pseudouridine Synthesis SnRNA Pseudouridine Synthesis Positive Regulation Of Telomere Maintenance Via Telomerase Box H/ACA Sno(s)RNA Metabolic Process Ribosome Biogenesis ScaRNA Localization To Cajal Body Telomerase RNA Stabilization Protein Localization To Cajal Body Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body Telomerase Holoenzyme Complex Assembly MRNA Pseudouridine Synthesis
Pathways		SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes	Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol
Drugs
Diseases			Hoyeraal-Hreidarsson syndrome Dyskeratosis congenita (DC), including: X-linked dyskeratosis congenita (DKCX); Autosomal dominant dyskeratosis congenita (DKCA1); Autosomal recessive dyskeratosis congenita (DKCB1)
GWAS		Brain morphology (MOSTest) ( 32665545) Ewing sarcoma ( 30093639) Hip circumference adjusted for BMI ( 34021172) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 24509480 28869590 30718926 32499647)
Interacting Genes		9 interacting genes: DKC1 EEF1A1 HSPA13 NPC2 NUP54 ODC1 PTN SERPINF2 UTP14A	10 interacting genes: CSNK2A1 DAXX EEF1G EIF3F ERG LYPLA2 MAPK6 RUVBL1 SSR1 TERC
Entrez ID		6745	1736
HPRD ID		02924	02129
Ensembl ID		ENSG00000124783	ENSG00000130826
Uniprot IDs		C9JBX5 P43307	A0A8Q3SIY6 O60832
PDB IDs		8B6L	7BGB 7TRC 7V9A 8OUE 8OUF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?