RUSC2

Description		RUN and SH3 domain containing 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Psoriasis ( 25903422)
Novel Interacting Genes		12 novel interacting genes: DLST EGFR FXR1 GIT2 GOLGA2 KHDRBS1 KLC2 MAGEC1 RAB1A RAB1B SIGMAR1 SRPRA
Interacting Genes		12 interacting genes: DLST EGFR FXR1 GIT2 GOLGA2 KHDRBS1 KLC2 MAGEC1 RAB1A RAB1B SIGMAR1 SRPRA
Entrez ID		9853
HPRD ID		18009
Ensembl ID		ENSG00000198853
Uniprot IDs		Q8N2Y8
PDB IDs		6IF2
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Metabolic Process Virion Assembly Cadherin Binding Establishment Of Endothelial Intestinal Barrier Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Regulation Of Protein Metabolic Process Establishment Of Endothelial Barrier Endothelial Cell Development Dihydrolipoyllysine-residue Succinyltransferase Activity Multivesicular Body, Internal Vesicle Lumen Grb2-Sos Complex Kinesin I Complex Golgi Membrane Golgi Vesicle Transport Establishment Of Protein Localization Organelle Assembly G Protein Activity GTPase Activity Shc-EGFR Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Oxoadipate Dehydrogenase Complex Positive Regulation Of Protein Kinase C Signaling Negative Regulation Of Catabolic Process Epidermal Growth Factor Receptor Activity Autophagosome Assembly GTP Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Autophagosome Organization L-lysine Catabolic Process Membrane Epidermal Growth Factor Binding Positive Regulation Of Protein Glycosylation Establishment Of Localization In Cell Signal Recognition Particle Receptor Complex
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