SP2 and QRICH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SP2	QRICH1
Description		Sp2 transcription factor	glutamine rich 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus Cytoplasm Plasma Membrane Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Histone Deacetylase Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Immune Response	Response To Unfolded Protein Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress PERK-mediated Unfolded Protein Response Positive Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Integrated Stress Response Signaling
Pathways
Drugs
Diseases
GWAS		Asthma with severe exacerbations ( 32841424) Birth weight ( 27680694) Blond vs. brown/black hair color ( 30531825) Body mass index ( 26426971) Childhood body mass index ( 33045005) Hair color ( 29662168)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Femur bone mineral density x serum urate levels interaction ( 34046847) General factor of neuroticism ( 30867560) Inflammatory bowel disease ( 28067908) Refractive error ( 32231278) Resting heart rate ( 27798624) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		11 interacting genes: APP BANP CINP E2F1 FHL2 MCM7 NFYC NKX3-1 NRF1 QRICH1 ZDHHC17	60 interacting genes: ACTL9 ACTMAP ARID5A ATF7IP ATXN1 BICRAL CEACAM6 CIMIP2B CRX CRYAA CYSRT1 DNAAF6 DSCR9 ELP6 FHL2 FHL3 FHL5 GMCL1 HIVEP1 HSFY1 HSPB8 IP6K2 KHDC4 KIAA1143 KLHDC7B LASP1 LBX1 LHX3 LHX4 LMO3 LMO4 MEOX1 MYH7B NFIX NFYA NLK P4HTM PAX6 PIERCE2 POGZ POU6F2 PRKAR1B PUF60 RBM17 SELENOV SEPHS1 SIAH1 SMAP1 SP2 SRARP TEKT5 TMA7 TOX4 TRAF1 TRAF2 USP54 YPEL3 ZDHHC17 ZMAT1 ZYX
Entrez ID		6668	54870
HPRD ID		03481	13372
Ensembl ID		ENSG00000167182	ENSG00000198218
Uniprot IDs		Q02086	A1L3Z9 Q2TAL8
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Binding Cellular Response To Xenobiotic Stimulus Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Response To Nerve Growth Factor Amylin Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Programmed Cell Death Nucleus Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Nerve Growth Factor Stimulus Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity Positive Regulation Of Androgen Secretion MADS Box Domain Binding Perforant Pathway To Dendrate Granule Cell Synapse Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Xenobiotic Stimulus Acetylcholine Receptor Activator Activity Response To Interleukin-1 Regulation Of DNA-templated Transcription Response To Growth Factor Regulation Of RNA Biosynthetic Process Regulation Of Apoptotic Process Lipoprotein Particle Positive Regulation Of Protein Import DNA Damage Response Atrial Cardiac Muscle Cell Development Dorsal Aorta Development Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Stress	Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Chromatin Medial Motor Column Neuron Differentiation Cell Differentiation In Spinal Cord Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of RNA Metabolic Process Motor Neuron Axon Guidance Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Transcription Regulator Complex DNA Binding Spinal Cord Motor Neuron Cell Fate Specification DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Nucleobase-containing Compound Metabolic Process Thioesterase Binding Spinal Cord Association Neuron Differentiation HMG Box Domain Binding
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