QRICH1 and MYH7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		QRICH1	MYH7B
Description		glutamine rich 1	myosin heavy chain 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane	Cytoplasm Membrane Myosin Complex Myosin II Complex Myofibril Myosin Filament Cardiac Myofibril
	Molecular Function	DNA Binding Protein Binding	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding ATP Binding Actin Filament Binding
	Biological Process	Response To Unfolded Protein Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress PERK-mediated Unfolded Protein Response Positive Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Integrated Stress Response Signaling	Regulation Of Calcium-mediated Signaling Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cardiac Muscle Cell Contraction Regulation Of CAMKK-AMPK Signaling Cascade
Pathways
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Femur bone mineral density x serum urate levels interaction ( 34046847) General factor of neuroticism ( 30867560) Inflammatory bowel disease ( 28067908) Refractive error ( 32231278) Resting heart rate ( 27798624) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172)	Alanine aminotransferase levels ( 34315874) Anticoagulant levels ( 22216198) Aspartate aminotransferase levels ( 34315874 33547301) Bipolar disorder ( 31043756) Birth weight ( 31043758) Congenital left-sided heart lesions ( 26965164) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462) Fish- and plant-related diet ( 32066663) Melanoma ( 28212542) Offspring birth weight ( 31043758) Prothrombin time ( 22703881) QRS complex (Cornell) ( 27659466) QRS duration ( 30012220) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		60 interacting genes: ACTL9 ACTMAP ARID5A ATF7IP ATXN1 BICRAL CEACAM6 CIMIP2B CRX CRYAA CYSRT1 DNAAF6 DSCR9 ELP6 FHL2 FHL3 FHL5 GMCL1 HIVEP1 HSFY1 HSPB8 IP6K2 KHDC4 KIAA1143 KLHDC7B LASP1 LBX1 LHX3 LHX4 LMO3 LMO4 MEOX1 MYH7B NFIX NFYA NLK P4HTM PAX6 PIERCE2 POGZ POU6F2 PRKAR1B PUF60 RBM17 SELENOV SEPHS1 SIAH1 SMAP1 SP2 SRARP TEKT5 TMA7 TOX4 TRAF1 TRAF2 USP54 YPEL3 ZDHHC17 ZMAT1 ZYX	8 interacting genes: ETFDH FOXP1 PITX1 QRICH1 RBPMS SMYD1 TLE5 TNS2
Entrez ID		54870	57644
HPRD ID		13372	11379
Ensembl ID		ENSG00000198218	ENSG00000078814
Uniprot IDs		A1L3Z9 Q2TAL8	A7E2Y1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Chromatin Medial Motor Column Neuron Differentiation Cell Differentiation In Spinal Cord Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of RNA Metabolic Process Motor Neuron Axon Guidance Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Transcription Regulator Complex DNA Binding Spinal Cord Motor Neuron Cell Fate Specification DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Nucleobase-containing Compound Metabolic Process Thioesterase Binding Spinal Cord Association Neuron Differentiation HMG Box Domain Binding
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