BNIP3 and MAP1LC3B

Number of citations of the paper that reports this interaction (PubMedID 23209295)
57

Data Source:
BioGRID (pull down)

		BNIP3	MAP1LC3B
Description		BCL2 interacting protein 3	microtubule associated protein 1 light chain 3 beta
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Postsynaptic Density Membrane Dendrite Mitochondrial Membrane	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Cytosol Cytoskeleton Microtubule Axoneme Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Mitochondrial Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding Endoplasmic Reticulum-autophagosome Adaptor Activity Mitochondrion Autophagosome Adaptor Activity	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding Ceramide Binding
	Biological Process	Autophagy Of Mitochondrion Mitophagy Response To Hypoxia Apoptotic Process Response To Bacterium Positive Regulation Of Autophagy Negative Regulation Of Mitochondrial Fusion Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Cerebral Cortex Development Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Positive Regulation Of Protein-containing Complex Disassembly Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Membrane Potential Regulation Of Mitochondrial Membrane Permeability Autophagic Cell Death Response To Axon Injury Oligodendrocyte Differentiation Brown Fat Cell Differentiation Neuron Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Defense Response To Virus Response To Hyperoxia Reticulophagy Substrate Localization To Autophagosome Cellular Response To Hydrogen Peroxide Cellular Response To Mechanical Stimulus Cellular Response To Cobalt Ion Cellular Response To Hypoxia Reactive Oxygen Species Metabolic Process Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxygen-glucose Deprivation Intrinsic Apoptotic Signaling Pathway Mitochondrial Outer Membrane Permeabilization Granzyme-mediated Programmed Cell Death Signaling Pathway Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Autophagy Of Mitochondrion Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation
Pathways			Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex SARS-CoV-2 modulates autophagy KEAP1-NFE2L2 pathway
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolite levels ( 23823483)	General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		72 interacting genes: AGTR1 AMIGO1 ARL13B BCL2 BCL2L1 BCL2L2 BIK BNIP2 BNIP3L CD3E CD47 CLDN9 CLEC7A CLN8 CMTM5 CREB3 CREB3L1 EBAG9 EBP ELOVL4 ERGIC3 FAM209A FAM241B FATE1 FBXL4 FFAR2 FXYD6-FXYD2 GPR152 GPR37 GPR42 HIF1A HIVEP1 HPN HTR2B IFNGR2 JAGN1 KTN1 LDLRAD1 LMNA MALL MAP1LC3B MS4A3 NCBP1 OPA1 PLP2 PPTC7 REEP2 RHEB RNASEK RNF24 RPRM SCN3B SEC22A SEC23A SLC31A2 SLC35B1 SLC6A17 SLC71A2 SMIM3 SPACA1 TGM2 TLCD4 TM4SF18 TMEM101 TMEM106C TMEM11 TMEM205 TMPRSS2 TMX2 TNMD TUBGCP2 ZDHHC15	97 interacting genes: AAMP ABTB3 ADD1 ADNP AFTPH AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BAG6 BIRC6 BNIP3 BRD3 BRD9 CAMSAP1 CARS2 CASP8 CCDC50 CCPG1 CCSER2 CDC37 CLTA CUL3 DBI DBN1 DNMT3B DPPA4 EED EPS8 EVA1A FLCN FUNDC1 GORASP2 HYPK IRGQ KBTBD7 KLHL5 KXD1 LUC7L2 MESD MKRN1 MRFAP1 MRTFA MTX1 MYBL2 NCOR1 NEDD4 NEK9 OPTN PCNT PLEKHM1 PRKCZ PRUNE2 RAD1 RAP1GAP RASAL3 RETREG1 RETREG2 RIC1 RIPOR1 RPLP1 SAMM50 SEM1 SEPTIN3 SMARCB1 SNCA SNU13 SNX18 SPAG9 SQSTM1 STK3 STK36 TAF7 TBC1D17 TBC1D25 TBC1D5 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 TPPP TRIM21 TRIM25 TRIM32 TTN UPF2 USP10 VHL WDR90
Entrez ID		664	81631
HPRD ID		04482	14358
Ensembl ID		ENSG00000176171	ENSG00000140941
Uniprot IDs		Q12983 Q6NVY4	Q658J6 Q9GZQ8
PDB IDs		2J5D 2KA1 2KA2	1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04 6LAN 7ELG 7GA8 7GA9 7GAA 7GAB 7GAC 7GAD 7GAE 7GAF 7GAG 7GAH 7GAI 7GAJ 7GAK 7GAL 7GAM 7GAN 7GAO 7GAP 7GAQ 7GAR 7GAS 7GAU 8Q53 8Q7K 8YV6
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Bcl-2 Family Protein Complex Protein Binding Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Mitochondrial Outer Membrane Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Mitochondrial Membrane Organization Apoptotic Mitochondrial Changes Negative Regulation Of Apoptotic Process Mitochondrial Membrane Mitochondrion Organization Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Programmed Cell Death Regulation Of Release Of Cytochrome C From Mitochondria Dendritic Cell Apoptotic Process Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Apoptotic Process Golgi Membrane Negative Regulation Of Autophagy Regulation Of Programmed Cell Death Release Of Cytochrome C From Mitochondria Regulation Of Intrinsic Apoptotic Signaling Pathway BH3 Domain Binding Apoptotic Process Membrane Organization Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Programmed Cell Death Cell Death Positive Regulation Of Cell Maturation Negative Regulation Of Dendritic Cell Apoptotic Process Channel Activity Regulation Of Response To Endoplasmic Reticulum Stress Ceramide Binding Transmembrane Transport Chemical Homeostasis Mitochondrion	Autophagy Autophagy Of Mitochondrion Mitophagy Macroautophagy Autophagosome Autophagosome Assembly Autophagosome Organization Nucleophagy Organelle Organization Regulation Of Autophagy Vacuole Organization Organelle Assembly Piecemeal Microautophagy Of The Nucleus Protein-phosphatidylethanolamide Deconjugating Activity Microautophagy Catabolic Process Positive Regulation Of Autophagy Protein Delipidation Aggrephagy Cellular Component Assembly Establishment Of Protein Localization Cytoplasm Substrate Localization To Autophagosome Intracellular Protein Localization Protein Transport Protein Binding Positive Regulation Of Catabolic Process Cytosol Endoplasmic Reticulum-autophagosome Adaptor Activity Cellular Localization Establishment Of Localization In Cell Regulation Of Protein Stability Proteolysis Involved In Protein Catabolic Process Cysteine-type Endopeptidase Activity Regulation Of Cellular Component Organization Response To Mitochondrial Depolarisation Proteolysis Regulation Of Organelle Organization Regulation Of Macroautophagy Protein Monoubiquitination GTPase Activator Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Macroautophagy Phagophore Assembly Site Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Catabolic Process Regulation Of Cell Projection Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?