MAP1LC3B and DBN1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	DBN1
Description		microtubule associated protein 1 light chain 3 beta	drebrin 1
Image
GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Cytosol Cytoskeleton Microtubule Axoneme Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Mitochondrial Membrane	Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Gap Junction Cell Cortex Postsynaptic Density Actin Cytoskeleton Membrane Dendrite Growth Cone Cortical Cytoskeleton Actomyosin Cell Projection Neuron Projection Postsynaptic Membrane Anchoring Junction Cell Periphery Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding Ceramide Binding	Actin Binding Protein Binding Profilin Binding Cadherin Binding Protein Sequestering Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation	In Utero Embryonic Development Actin Filament Organization Nervous System Development Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Cell Differentiation Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Regulation Of Neuronal Synaptic Plasticity Generation Of Neurons Regulation Of Dendrite Development Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Positive Regulation Of Receptor Localization To Synapse
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex SARS-CoV-2 modulates autophagy KEAP1-NFE2L2 pathway	RHOD GTPase cycle RHOH GTPase cycle RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261) Refractive error ( 32231278)	Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		97 interacting genes: AAMP ABTB3 ADD1 ADNP AFTPH AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BAG6 BIRC6 BNIP3 BRD3 BRD9 CAMSAP1 CARS2 CASP8 CCDC50 CCPG1 CCSER2 CDC37 CLTA CUL3 DBI DBN1 DNMT3B DPPA4 EED EPS8 EVA1A FLCN FUNDC1 GORASP2 HYPK IRGQ KBTBD7 KLHL5 KXD1 LUC7L2 MESD MKRN1 MRFAP1 MRTFA MTX1 MYBL2 NCOR1 NEDD4 NEK9 OPTN PCNT PLEKHM1 PRKCZ PRUNE2 RAD1 RAP1GAP RASAL3 RETREG1 RETREG2 RIC1 RIPOR1 RPLP1 SAMM50 SEM1 SEPTIN3 SMARCB1 SNCA SNU13 SNX18 SPAG9 SQSTM1 STK3 STK36 TAF7 TBC1D17 TBC1D25 TBC1D5 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 TPPP TRIM21 TRIM25 TRIM32 TTN UPF2 USP10 VHL WDR90	30 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HNRNPAB HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 OGT PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 USP7 ZNF598
Entrez ID		81631	1627
HPRD ID		14358	00545
Ensembl ID		ENSG00000140941	ENSG00000113758
Uniprot IDs		Q658J6 Q9GZQ8	Q16643
PDB IDs		1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04 6LAN 7ELG 7GA8 7GA9 7GAA 7GAB 7GAC 7GAD 7GAE 7GAF 7GAG 7GAH 7GAI 7GAJ 7GAK 7GAL 7GAM 7GAN 7GAO 7GAP 7GAQ 7GAR 7GAS 7GAU 8Q53 8Q7K 8YV6	5Y1Z 5ZZ9
Enriched GO Terms of Interacting Partners?		Autophagy Autophagy Of Mitochondrion Mitophagy Macroautophagy Autophagosome Autophagosome Assembly Autophagosome Organization Nucleophagy Organelle Organization Regulation Of Autophagy Vacuole Organization Organelle Assembly Piecemeal Microautophagy Of The Nucleus Protein-phosphatidylethanolamide Deconjugating Activity Microautophagy Catabolic Process Positive Regulation Of Autophagy Protein Delipidation Aggrephagy Cellular Component Assembly Establishment Of Protein Localization Cytoplasm Substrate Localization To Autophagosome Intracellular Protein Localization Protein Transport Protein Binding Positive Regulation Of Catabolic Process Cytosol Endoplasmic Reticulum-autophagosome Adaptor Activity Cellular Localization Establishment Of Localization In Cell Regulation Of Protein Stability Proteolysis Involved In Protein Catabolic Process Cysteine-type Endopeptidase Activity Regulation Of Cellular Component Organization Response To Mitochondrial Depolarisation Proteolysis Regulation Of Organelle Organization Regulation Of Macroautophagy Protein Monoubiquitination GTPase Activator Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Macroautophagy Phagophore Assembly Site Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Catabolic Process Regulation Of Cell Projection Assembly	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Organelle Organization Negative Regulation Of Macromolecule Metabolic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomere Lengthening Nucleoplasm Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Negative Regulation Of Biosynthetic Process RNA-templated DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Nucleus Regulation Of DNA Biosynthetic Process Cellular Component Assembly Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Cellular Component Organization Telomere Maintenance DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Chromosome Organization Nuclear Body Regulation Of Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Cytoplasm Cytosol Rhythmic Process Nucleic Acid Metabolic Process Telomere Organization Negative Regulation Of DNA Metabolic Process Telomeric D-loop Disassembly Vagina Development G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
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