TRAK2 and NIF3L1

		TRAK2	NIF3L1
Description		trafficking kinesin protein 2	NGG1 interacting factor 3 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Endosome Early Endosome Cytosol Plasma Membrane Dendrite Cytoplasmic Vesicle Dendrite Cytoplasm Neuronal Cell Body Axonal Growth Cone	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Signaling Receptor Binding Protein Binding Myosin Binding Kinesin Binding Enzyme Binding TPR Domain Binding GABA Receptor Binding	Protein Binding Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Endosome To Lysosome Transport Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Dendrite Morphogenesis Negative Regulation Of Axonogenesis Dendritic Transport Of Mitochondrion	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Neuron Differentiation Positive Regulation Of DNA-templated Transcription
Pathways		RHOT2 GTPase cycle RHOT1 GTPase cycle
Drugs
Diseases
GWAS		Breast cancer ( 31757997) Cocaine use disorder x change in residence interaction ( 31490055)	Triptolide cytotoxicity ( 26121980)
Interacting Genes		6 interacting genes: EIF4ENIF1 GABRB2 KCNJ2 NIF3L1 OGT TAFAZZIN	100 interacting genes: ABI2 ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CXCL12 CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 ICOS IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KLRC2 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RAPH1 RGMB RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRAK2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1
Entrez ID		66008	60491
HPRD ID		09547	10424
Ensembl ID		ENSG00000115993	ENSG00000196290
Uniprot IDs		O60296	Q9GZT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Relaxation Of Skeletal Muscle Positive Regulation Of Cardiolipin Metabolic Process Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA GABA Receptor Activity Dendritic Spine Cellular Response To Histamine Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Positive Regulation Of Lipid Metabolic Process Regulation Of Cardiolipin Metabolic Process Mitochondrial Membrane Cardiolipin Acyl-chain Remodeling 1-acylglycerophosphocholine O-acyltransferase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Negative Regulation Of Translation Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Carbon Catabolite Regulation Of Transcription Postsynaptic Membrane	Identical Protein Binding Cytoplasm Protein Binding Cytosol Protein Complex Oligomerization Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Ethanol Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Nucleoside Phosphate Metabolic Process Phosphate-containing Compound Metabolic Process Sulfation Pyrimidine Nucleotide Metabolic Process Polyamine Catabolic Process Nucleus Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination
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