NIF3L1 and RGMB

		NIF3L1	RGMB
Description		NGG1 interacting factor 3 like 1	repulsive guidance molecule BMP co-receptor b
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Membrane Membrane Raft Side Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Protein Binding Coreceptor Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Neuron Differentiation Positive Regulation Of DNA-templated Transcription	Cell Adhesion Signal Transduction Positive Regulation Of Macromolecule Metabolic Process BMP Signaling Pathway Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process
Pathways			Netrin-1 signaling
Drugs
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Asperger disorder ( 21182207) Loneliness (multivariate analysis) ( 27629369) Systolic blood pressure ( 30224653)
Interacting Genes		100 interacting genes: ABI2 ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CXCL12 CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 ICOS IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KLRC2 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RAPH1 RGMB RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRAK2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1	3 interacting genes: BMP2 BMP4 NIF3L1
Entrez ID		60491	285704
HPRD ID		10424	15243
Ensembl ID		ENSG00000196290	ENSG00000174136
Uniprot IDs		Q9GZT8	J3KNF6 Q6NW40
PDB IDs			4BQ6 4BQ7 4BQ8 4UHZ 4UI0 4UI2 6Z3H 6Z3J 6Z3M
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoplasm Protein Binding Cytosol Protein Complex Oligomerization Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Ethanol Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Nucleoside Phosphate Metabolic Process Phosphate-containing Compound Metabolic Process Sulfation Pyrimidine Nucleotide Metabolic Process Polyamine Catabolic Process Nucleus Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination	Cardiac Jelly Development Heart Induction Ameloblast Differentiation Telencephalon Regionalization Positive Regulation Of Odontoblast Differentiation Positive Regulation Of Neuroepithelial Cell Differentiation Regulation Of Odontogenesis Of Dentin-containing Tooth Regulation Of Heart Morphogenesis Regulation Of Odontoblast Differentiation Co-receptor Binding Lung Vasculature Development BMP Receptor Binding Regulation Of Odontogenesis Regulation Of Cardiac Muscle Cell Differentiation Organ Induction Developmental Induction Regulation Of Animal Organ Formation Cellular Response To BMP Stimulus Positive Regulation Of P38MAPK Cascade Neuron Differentiation Telencephalon Development Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Cartilage Development Cardiac Muscle Cell Differentiation Positive Regulation Of Bone Mineralization Regulation Of P38MAPK Cascade Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Cardiocyte Differentiation Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Ossification Heart Valve Morphogenesis Heart Morphogenesis Vasculature Development Negative Regulation Of Smooth Muscle Cell Proliferation Mesenchyme Development Chondrocyte Differentiation Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Epithelial Cell Differentiation Regulation Of SMAD Protein Signal Transduction Regulation Of Cartilage Development Striated Muscle Cell Differentiation Positive Regulation Of Osteoblast Differentiation Bone Development Odontogenesis Of Dentin-containing Tooth Protein Serine/threonine Kinase Activator Activity Muscle Tissue Morphogenesis Regulation Of MiRNA Transcription Regulation Of Bone Mineralization Regulation Of Animal Organ Morphogenesis
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