ACD and PFKP

Number of citations of the paper that reports this interaction (PubMedID 21044950)
82

Data Source:
BioGRID (two hybrid)

		ACD	PFKP
Description		ACD shelterin complex subunit and telomerase recruitment factor	phosphofructokinase, platelet
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Chromosome Telomerase Holoenzyme Complex Nuclear Body Shelterin Complex	Nucleus Cytoplasm Cytosol 6-phosphofructokinase Complex Membrane Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Telomerase Inhibitor Activity Telomeric DNA Binding Protein-containing Complex Binding DNA Polymerase Binding	Nucleotide Binding Catalytic Activity 6-phosphofructokinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Identical Protein Binding Protein-containing Complex Binding Cadherin Binding Metal Ion Binding Fructose-6-phosphate Binding
	Biological Process	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Maintenance Via Telomerase Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Protein Localization To Chromosome, Telomeric Region Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Telomere	Fructose 6-phosphate Metabolic Process Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Canonical Glycolysis Cellular Response To Leukemia Inhibitory Factor
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Telomere C-strand synthesis initiation Removal of the Flap Intermediate from the C-strand DNA Damage/Telomere Stress Induced Senescence Inhibition of DNA recombination at telomere	Glycolysis
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Body size at age 10 ( 32376654) Disc degeneration (lumbar) ( 22993228) HDL cholesterol levels in HIV infection ( 33109212) Hippocampal volume in mild cognitive impairment ( 29274321) Mean platelet volume ( 32888494) Scalp hair shape ( 26926045) Subclinical trait of interstitial lung disease (percentage of high attenuation areas on CT scan) ( 28521775)
Interacting Genes		65 interacting genes: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 ANXA8L1 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA ESRP2 FAM131B FBXW7 FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NTAQ1 NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TRIM55 TRIM63 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	16 interacting genes: ACD AGO2 AKT1 DYNLL1 EGFR IL2RA KAT5 LINC00632 NUTF2 POT1 SUMO2 TERF1 TINF2 TRIM21 VHL WNK1
Entrez ID		65057	5214
HPRD ID		12417	01384
Ensembl ID		ENSG00000102977	ENSG00000067057
Uniprot IDs		A0A8Q3WM11 Q96AP0	A0A7I2V3Z0 A0A8V8TMY4 B1APP6 Q01813
PDB IDs		2I46 5H65 5I2X 5I2Y 5UN7 5XYF 7QXA 7QXB 7QXS 7S1T 7TRE 8SOJ 8SOK	4RH3 4U1R 4WL0 4XYJ 4XYK 4XZ2 7TFF
Enriched GO Terms of Interacting Partners?		Cytoplasm Cytosol Cadherin Binding Carbohydrate Catabolic Process Nuclear Telomere Cap Complex Protein Folding Chaperone Complex Substantia Nigra Development ADP Catabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Glycolytic Process Telomere Maintenance Cellular Response To Heat ADP Metabolic Process Nicotinamide Nucleotide Metabolic Process Nucleoside Diphosphate Catabolic Process Monosaccharide Metabolic Process Ribonucleoside Diphosphate Catabolic Process Unfolded Protein Binding Telomeric D-loop Binding Telomere Assembly Organelle Organization Neural Nucleus Development Pyruvate Metabolic Process Glucose Metabolic Process Telomere Organization Protein Folding Cortical Cytoskeleton Glucose Catabolic Process Telomeric DNA Binding Protein Binding Shelterin Complex Ribonucleoside Diphosphate Metabolic Process Purine Ribonucleotide Catabolic Process Structural Constituent Of Postsynaptic Actin Cytoskeleton Cytoskeleton Organization Cytoskeleton Microtubule Cytoskeleton Organization Nucleoside Diphosphate Metabolic Process Protein Stabilization Chaperone-mediated Autophagy Microtubule Response To Heat Purine Nucleotide Catabolic Process Nitric-oxide Synthase Regulator Activity TPR Domain Binding Hexose Metabolic Process Microtubule Cytoskeleton Intercellular Bridge Telomeric D-loop Disassembly Hsp90 Protein Binding	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Assembly Regulation Of DNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Macromolecule Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Regulation Of DNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process RNA-templated DNA Biosynthetic Process Telomere Maintenance Regulation Of Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of Telomere Maintenance Positive Regulation Of Metabolic Process Positive Regulation Of Organelle Organization Telomere Organization Positive Regulation Of Cell Cycle Establishment Of Protein Localization To Organelle Regulation Of Establishment Of Protein Localization To Telomere Organelle Organization Activation-induced Cell Death Of T Cells Regulation Of Autophagy Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Regulation Of Primary Metabolic Process Negative Regulation Of Catabolic Process Chromosome, Telomeric Region Nitric-oxide Synthase Regulator Activity Chromosome Telomeric D-loop Disassembly DNA Metabolic Process Positive Regulation Of Cellular Component Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?