IL25 and IL17RB

Number of citations of the paper that reports this interaction (PubMedID 11058597)
0

Data Source:
HPRD (in vitro, in vivo)

		IL25	IL17RB
Description		interleukin 25	interleukin 17 receptor B
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Interleukin-17E Receptor Binding	Cytokine Receptor Activity Protein Binding Interleukin-17 Receptor Activity
	Biological Process	Inflammatory Response To Antigenic Stimulus Inflammatory Response Signal Transduction Response To Fungus Response To Nematode Eosinophil Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Cell Growth Defense Response Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Inflammatory Response
Pathways		Interleukin-17 signaling	Interleukin-17 signaling
Drugs
Diseases
GWAS		PR interval ( 30046033 32439900)	Axial length ( 24144296) Body mass index ( 26426971) interleukin 17 receptor B levels ( 25147954) Refractive error ( 32231278) Response to tofacitinib treatment (herpes zoster) ( 33455090) Response to tofacitinib treatment (herpes zoster)(time to event) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster)(time to event) ( 33455090)
Interacting Genes		1 interacting genes: IL17RB	4 interacting genes: IL17B IL25 RPS6KA5 TRAF6
Entrez ID		64806	55540
HPRD ID		05742	05677
Ensembl ID		ENSG00000166090	ENSG00000056736
Uniprot IDs		Q9H293	Q9NRM6
PDB IDs		7UWJ 7UWK 7UWL	7UWJ 7UWK 7UWL
Enriched GO Terms of Interacting Partners?		Interleukin-17 Receptor Activity Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-13 Production Cytokine Receptor Activity	Interleukin-1-mediated Signaling Pathway Defense Response Positive Regulation Of NF-kappaB Transcription Factor Activity Inflammatory Response Positive Regulation Of DNA-binding Transcription Factor Activity Histone H2AS1 Kinase Activity Interleukin-17E Receptor Binding Myeloid Leukocyte Differentiation Regulation Of Cytokine Production Positive Regulation Of Macromolecule Biosynthetic Process Histone H3S28 Kinase Activity Positive Regulation Of Biosynthetic Process Regulation Of DNA-binding Transcription Factor Activity Histone H3S10 Kinase Activity Cytokine Activity Positive Regulation Of Macromolecule Metabolic Process Response To Stress Immune Response Interleukin-17A-mediated Signaling Pathway Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Eosinophil Differentiation Positive Regulation Of Metabolic Process CD40 Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Protein Kinase B Binding Interleukin-33-mediated Signaling Pathway T-helper 1 Type Immune Response Interleukin-17-mediated Signaling Pathway Positive Regulation Of CREB Transcription Factor Activity Response To Nematode Positive Regulation Of JUN Kinase Activity Leukocyte Differentiation Cytokine-mediated Signaling Pathway Positive Regulation Of RNA Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of DNA-templated Transcription Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane MyD88-dependent Toll-like Receptor Signaling Pathway Ubiquitin-ubiquitin Ligase Activity Signal Transduction Bone Remodeling Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Myeloid Dendritic Cell Differentiation Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of RNA Metabolic Process Protein Branched Polyubiquitination
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