IL17RB

Description		interleukin 17 receptor B
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Membrane
	Molecular Function	Cytokine Receptor Activity Protein Binding Interleukin-17 Receptor Activity
	Biological Process	Regulation Of Cell Growth Defense Response Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Inflammatory Response
Pathways		Interleukin-17 signaling
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) interleukin 17 receptor B levels ( 25147954) Refractive error ( 32231278) Response to tofacitinib treatment (herpes zoster) ( 33455090) Response to tofacitinib treatment (herpes zoster)(time to event) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster)(time to event) ( 33455090)
Novel Interacting Genes		4 novel interacting genes: IL17B IL25 RPS6KA5 TRAF6
Interacting Genes		4 interacting genes: IL17B IL25 RPS6KA5 TRAF6
Entrez ID		55540
HPRD ID		05677
Ensembl ID		ENSG00000056736
Uniprot IDs		Q9NRM6
PDB IDs		7UWJ 7UWK 7UWL
Enriched GO Terms of Interacting Partners?		Interleukin-1-mediated Signaling Pathway Defense Response Positive Regulation Of NF-kappaB Transcription Factor Activity Inflammatory Response Positive Regulation Of DNA-binding Transcription Factor Activity Histone H2AS1 Kinase Activity Interleukin-17E Receptor Binding Myeloid Leukocyte Differentiation Regulation Of Cytokine Production Positive Regulation Of Macromolecule Biosynthetic Process Histone H3S28 Kinase Activity Positive Regulation Of Biosynthetic Process Regulation Of DNA-binding Transcription Factor Activity Histone H3S10 Kinase Activity Cytokine Activity Positive Regulation Of Macromolecule Metabolic Process Response To Stress Immune Response Interleukin-17A-mediated Signaling Pathway Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Eosinophil Differentiation Positive Regulation Of Metabolic Process CD40 Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Protein Kinase B Binding Interleukin-33-mediated Signaling Pathway T-helper 1 Type Immune Response Interleukin-17-mediated Signaling Pathway Positive Regulation Of CREB Transcription Factor Activity Response To Nematode Positive Regulation Of JUN Kinase Activity Leukocyte Differentiation Cytokine-mediated Signaling Pathway Positive Regulation Of RNA Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of DNA-templated Transcription Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane MyD88-dependent Toll-like Receptor Signaling Pathway Ubiquitin-ubiquitin Ligase Activity Signal Transduction Bone Remodeling Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Myeloid Dendritic Cell Differentiation Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of RNA Metabolic Process Protein Branched Polyubiquitination
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