RMND5B and SHBG

Number of citations of the paper that reports this interaction (PubMedID 15862967)
0

Data Source:
HPRD (two hybrid)

		RMND5B	SHBG
Description		required for meiotic nuclear division 5 homolog B	sex hormone binding globulin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol GID Complex	Extracellular Region Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Steroid Binding Androgen Binding Protein Binding Lipid Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Regulation of pyruvate metabolism
Drugs			Masoprocol Diethylstilbestrol Levonorgestrel Progesterone Spironolactone Toremifene Estrone Tamoxifen Clomifene Dienestrol Hesperetin Zinc Genistein Naringenin Quercetin 4'-Hydroxyflavanone Afimoxifene Estriol Phenolphthalein Norethynodrel Dioxybenzone Zeranol Gestrinone Equol Zinc acetate Zinc chloride Zinc sulfate, unspecified form Estriol tripropionate
Diseases
GWAS			A body shape index ( 34021172) Androgen levels ( 22936694) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Estradiol levels ( 34255042) Glycated hemoglobin levels ( 34059833) Heel bone mineral density ( 30598549) Hormone measurements ( 24049095) Medication use (calcium channel blockers) ( 31015401) Protein quantitative trait loci ( 18464913) Red cell distribution width ( 27863252) Refractive error ( 32231278) Sex hormone levels ( 26014426) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: CDK9 EWSR1 SHBG SMAD4 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2W	62 interacting genes: A2M ACP3 ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5F1A AZGP1 CD177 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HDHD5 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SPMIP6 SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A
Entrez ID		64777	6462
HPRD ID		07985	01646
Ensembl ID		ENSG00000145916	ENSG00000129214
Uniprot IDs		B3KSG5 F5H6G4 Q96G75	B0FWH2 B0FWH8 I3L145 P04278
PDB IDs			1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW 6PYA 6PYB 6PYF 6ULB
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein K11-linked Ubiquitination Protein Monoubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation ATP Binding Post-translational Protein Modification Protein Modification Process Nucleotide Binding Transferase Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Protein K6-linked Ubiquitination Macromolecule Catabolic Process Nucleoplasm Proteolysis Protein Metabolic Process Transcription Coactivator Binding Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Protein Autoubiquitination Protein K63-linked Ubiquitination Nucleus Macromolecule Metabolic Process P-TEFb Complex Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Positive Regulation Of Protein Localization To Chromatin Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Metanephric Mesenchyme Morphogenesis Positive Regulation Of Luteinizing Hormone Secretion ISG15 Transferase Activity Transcription Pausing By RNA Polymerase II DNA Repair Sulfate Binding Endocardial Cell Differentiation Androgen Binding Catabolic Process Negative Regulation Of Protein Localization To Chromatin Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis ISG15-protein Conjugation Regulation Of Muscle Cell Differentiation	Extracellular Exosome Protease Binding Cell-cell Junction Fructose Biosynthetic Process Detoxification Of Copper Ion Extracellular Space Glucose 6-phosphate:phosphate Antiporter Activity Cellular Response To Cadmium Ion Lamellipodium Cellular Response To Zinc Ion Cellular Response To Copper Ion Mesenchyme Migration Glucose-6-phosphate Transport Negative Regulation Of Cardiac Muscle Contraction Intracellular Zinc Ion Homeostasis Prostaglandin Metabolic Process Prostanoid Metabolic Process Response To Copper Ion Rough Endoplasmic Reticulum Hexose Metabolic Process Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Striated Muscle Contraction Response To Cadmium Ion Cell-cell Junction Organization Caveola Assembly Carbohydrate Metabolic Process Monosaccharide Metabolic Process Plasma Membrane Raft Assembly Response To Zinc Ion
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