ZNF574 and B9D2

		ZNF574	B9D2
Description		zinc finger protein 574	B9 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cilium Membrane MKS Complex Ciliary Basal Body Cell Projection
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Developmental Process	Cell Projection Organization Cilium Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Meat-related diet ( 32066663)	Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 29212778 32469254) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)
Interacting Genes		10 interacting genes: APP B9D2 CEP70 DCDC2B FBXO7 GOLGA6L9 LHX3 MEOX2 POU6F2 TRAF2	15 interacting genes: ALKBH7 CCDC97 CCNP CEACAM21 CNFN P4HA3 PLEKHA7 PLEKHG2 QARS1 SAXO4 SPAG8 TLX3 VPS25 YIF1B ZNF574
Entrez ID		64763	80776
HPRD ID		15853	14613
Ensembl ID		ENSG00000105732	ENSG00000123810
Uniprot IDs		A0A0C4DFM2 Q6ZN55 Q71MF7	Q9BPU9
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway TORC2 Complex Disassembly Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Gamma-tubulin Binding Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Ubiquitin Ligase Complex Sphingolipid Binding TRAF2-GSTP1 Complex IRE1-TRAF2-ASK1 Complex TORC1 Complex Assembly CD40 Receptor Binding Tumor Necrosis Factor Receptor Superfamily Complex Medial Motor Column Neuron Differentiation Ventral Spinal Cord Interneuron Specification Prolactin Secreting Cell Differentiation Somatotropin Secreting Cell Differentiation Lewy Body Core Microtubule Organizing Center Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cell Projection Organization Growth Factor Receptor Binding Main Axon
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