TMPPE and REEP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMPPE	REEP6
Description		transmembrane protein with metallophosphoesterase domain	receptor accessory protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Hydrolase Activity Metal Ion Binding	Protein Binding
	Biological Process		Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1	51 interacting genes: ADAT3 AQP6 ARL6IP1 ATP5PF BIK CD79A CDC37 CERT1 COQ8A CYB561 CYB5R3 EBAG9 FHIP1B GJA8 GORASP2 GPR152 HMBOX1 HSD17B13 IZUMO4 KRTAP3-1 LEPROTL1 LITAF LMNA LNX1 MIEF2 NDRG4 NTAQ1 PICK1 PTPN9 RPS20 SCAMP4 SDCBP SLC30A8 SNX1 SNX11 SNX15 SNX8 SPG21 STING1 SYT16 TIMMDC1 TLCD4 TMED8 TMEM143 TMEM259 TMPPE TNS2 TXN2 WIPI2 ZFYVE21 ZNF554
Entrez ID		643853	92840
HPRD ID		18951	16629
Ensembl ID		ENSG00000188167	ENSG00000115255
Uniprot IDs		Q6ZT21	A0A1L5BXV2 Q96HR9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Organelle Membrane Fusion SNAP Receptor Activity Vesicle Fusion SNARE Complex Organelle Fusion Membrane Fusion Vesicle Docking Endoplasmic Reticulum Organization Organelle Localization By Membrane Tethering External Side Of Plasma Membrane Membrane Docking	Lipid Binding Establishment Of Protein Localization Identical Protein Binding Membrane
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