SRSF3 and RBMY1A1

Number of citations of the paper that reports this interaction (PubMedID 10823932)
30

Data Source:
HPRD (two hybrid, in vitro)

		SRSF3	RBMY1A1
Description		serine and arginine rich splicing factor 3	RNA binding motif protein Y-linked family 1 member A1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding Phospholipase Binding Primary MiRNA Binding Protein-RNA Sequence-specific Adaptor Activity Sequence-specific MRNA Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing MRNA Export From Nucleus RNA Splicing Primary MiRNA Processing Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport Cellular Response To Leukemia Inhibitory Factor	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 33627673) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		40 interacting genes: - APP BCL2L13 CHD1 CIRBP CLK3 CNNM3 DUX4 EXOSC6 FOXP1 GEMIN2 HMGB1 HNRNPK IL7R LNX1 NXF1 PCBP1 PCBP2 PCBP3 PCDHB14 PRPF31 RBM3 RBM7 RBMY1A1 RNF10 RNPS1 RPL9 SCAF11 SDCBP SREK1 SRPK1 SRPK2 SRSF2 SRSF8 TRA2B U2AF1 U2AF2 YWHAB YWHAG YWHAQ	29 interacting genes: AEN APOBEC3C CBX2 CIRBP CLK3 DAAM2 DHX57 HBZ HNRNPK KHDRBS3 LMNTD2 LNX1 MYPOP PCDHB14 PRPF31 PRR3 RASD1 RBM3 RBMX RBMY1F RBMY1J SNRPA SRSF3 SRSF9 TERF1 TH TRA2B YTHDC1 ZNF317
Entrez ID		6428	5940
HPRD ID		04530	02450
Ensembl ID		ENSG00000112081	ENSG00000234414
Uniprot IDs		B2R6F3 P84103	P0DJD3
PDB IDs		2I2Y 2I38 9ASQ	2FY1
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome RNA Binding Regulation Of RNA Splicing Regulation Of MRNA Processing MRNA Metabolic Process RNA Splicing Nucleic Acid Binding MRNA Processing RNA Metabolic Process Regulation Of MRNA Metabolic Process Spliceosomal Complex RNA Processing Nucleus Nuclear Speck Nucleoplasm Nucleic Acid Metabolic Process MRNA Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Splicing Spliceosomal Complex Assembly Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Viral RNA Genome Replication Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Viral Genome Replication Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of RNA Splicing Positive Regulation Of Biosynthetic Process Focal Adhesion Negative Regulation Of RNA Metabolic Process 14-3-3 Protein Binding Pre-mRNA 3'-splice Site Binding U2AF Complex Negative Regulation Of MRNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Sequestering Activity Protein Domain Specific Binding Ribonucleoprotein Complex	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing Nucleic Acid Binding Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Binding MRNA Processing Positive Regulation Of RNA Splicing RNA Splicing RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Metabolic Process Positive Regulation Of MRNA Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Primary Metabolic Process Negative Regulation Of RNA Splicing Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleus Negative Regulation Of MRNA Metabolic Process Protein Domain Specific Binding Nucleoplasm Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Pre-mRNA Binding Negative Regulation Of Macromolecule Metabolic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Gene Expression Nuclear Speck Protein Binding Negative Regulation Of Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere
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