RBSN and RAB5A

Number of citations of the paper that reports this interaction (PubMedID 11062261)
57

Data Source:
HPRD (in vitro)

		RBSN	RAB5A
Description		rabenosyn, RAB effector	RAB5A, member RAS oncogene family
Image
GO Annotations	Cellular Component	Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Early Endosome Membrane Extracellular Exosome	Ruffle Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Synaptic Vesicle Endosome Membrane Endomembrane System Actin Cytoskeleton Membrane Endocytic Vesicle Axon Dendrite Clathrin-coated Endocytic Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Early Phagosome Somatodendritic Compartment Melanosome Cell Projection Neuronal Cell Body Terminal Bouton Axon Terminus Membrane Raft Phagocytic Vesicle Extracellular Exosome Cytoplasmic Side Of Early Endosome Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Small GTPase Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Guanyl Nucleotide Binding GDP Binding
	Biological Process	Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization	Intracellular Protein Transport Endocytosis Phagocytosis Protein Transport Endosomal Transport Receptor Internalization Synaptic Vesicle Recycling Host-mediated Perturbation Of Viral Process Early Endosome To Late Endosome Transport Positive Regulation Of Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Endosome Size Regulation Of Filopodium Assembly Canonical Wnt Signaling Pathway Membrane Fusion Amyloid-beta Clearance By Transcytosis Protein Localization To Early Endosome Regulation Of Synaptic Vesicle Exocytosis Regulation Of Autophagosome Assembly
Pathways		Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production	Synthesis of PIPs at the plasma membrane TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Prevention of phagosomal-lysosomal fusion Respiratory syncytial virus (RSV) attachment and entry Factors involved in megakaryocyte development and platelet production
Drugs			L-methionine (S)-S-oxide Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS			Heel bone mineral density ( 30598549) Iris color (L* coordinate) ( 30895295)
Interacting Genes		15 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 PSEN1 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45	37 interacting genes: AGTR1 ALS2CL ANKFY1 APPL1 APPL2 CHML EEA1 GDI2 GRIK4 HTATIP2 ITSN1 NME2 OCRL RAB37 RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 SNCA STX4 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TRIM14 TSC2 USP6NL WEE2-AS1
Entrez ID		64145	5868
HPRD ID		15732	01542
Ensembl ID		ENSG00000131381	ENSG00000144566
Uniprot IDs		A8K5H3 Q9H1K0	P20339
PDB IDs		1YZM 1Z0J 1Z0K	1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH 4Q9U 7BL1
Enriched GO Terms of Interacting Partners?		G Protein Activity Endosome GTP Binding Intracellular Protein Localization Protein Transport Establishment Of Localization In Cell Endocytic Vesicle Intracellular Transport Regulation Of Vesicle-mediated Transport GDP Binding Establishment Of Protein Localization Early Endosome Membrane Cellular Localization Regulation Of Transport Synaptic Vesicle Vesicle-mediated Transport Cytoplasmic Vesicle GTPase Activity Early Endosome Positive Regulation Of Myoblast Fusion Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Recycling Endosome Membrane Melanosome Endosomal Transport Endomembrane System Nucleotide Binding Endosome Membrane Intracellular Protein Transport Glutamatergic Synapse Positive Regulation Of Intracellular Transport Regulation Of Cellular Component Organization Azurophil Granule Membrane Lysosomal Membrane Regulation Of Dendritic Spine Development Perinuclear Region Of Cytoplasm Organelle Assembly Hydrolase Activity Positive Regulation Of Endocytic Recycling Plasma Membrane To Endosome Transport Regulation Of Synaptic Transmission, Glutamatergic Endocytic Recycling Positive Regulation Of Transport Cilium Assembly Regulation Of Intracellular Transport Organelle Organization Regulation Of Synaptic Vesicle Cycle Cilium Organization Regulation Of Synapse Organization Vesicle Organization	GTPase Activator Activity Small GTPase Binding Vesicle-mediated Transport Endosome Regulation Of Endocytosis Regulation Of Vesicle-mediated Transport Endocytosis Cytoplasmic Vesicle Regulation Of Cellular Component Organization Cellular Localization Import Into Cell Intracellular Transport Regulation Of Cilium Assembly Endosomal Transport Small GTPase-mediated Signal Transduction Macropinosome Establishment Of Protein Localization Protein Transport Early Endosome Membrane Cytosol Establishment Of Localization In Cell Positive Regulation Of Pinocytosis Regulation Of Transport Early Endosome Regulation Of Organelle Assembly Cytoplasm Positive Regulation Of Macropinocytosis Regulation Of Cell Projection Assembly Endocytic Vesicle Membrane Fusion Positive Regulation Of Endocytosis Rab-protein Geranylgeranyltransferase Complex Phagocytic Vesicle Signal Transduction Intracellular Protein Localization Vesicle Fusion Retrograde Transport, Endosome To Golgi Protein Geranylgeranylation Organelle Membrane Fusion Ruffle Guanyl-nucleotide Exchange Factor Activity Synapse Adiponectin-activated Signaling Pathway Regulation Of Organelle Organization Protein Prenylation Organelle Fusion Cytosolic Transport Plasma Membrane To Endosome Transport Recycling Endosome Cell Projection
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?