RBSN and RAB2A

Number of citations of the paper that reports this interaction (PubMedID 16034420)
30

Data Source:
HPRD (in vitro)

		RBSN	RAB2A
Description		rabenosyn, RAB effector	RAB2A, member RAS oncogene family
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GO Annotations	Cellular Component	Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Early Endosome Membrane Extracellular Exosome	Golgi Membrane Autophagosome Membrane Acrosomal Vesicle Nucleus Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Small GTPase Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Vesicle-mediated Transport Macroautophagy Autophagosome-lysosome Fusion
Pathways		Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production	Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS			Aspartate aminotransferase levels ( 33547301) Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		15 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 PSEN1 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45	32 interacting genes: ASPH BLZF1 CBFB CCDC125 CEBPA CFL2 CPA4 FAM114A1 FAM114A2 FRMD1 GAA GAPDH GARIN4 GARIN6 GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 OTOS PMAIP1 PRKCI RBSN RGS2 RP1 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		64145	5862
HPRD ID		15732	01539
Ensembl ID		ENSG00000131381	ENSG00000104388
Uniprot IDs		A8K5H3 Q9H1K0	P61019
PDB IDs		1YZM 1Z0J 1Z0K	1Z0A
Enriched GO Terms of Interacting Partners?		G Protein Activity Endosome GTP Binding Intracellular Protein Localization Protein Transport Establishment Of Localization In Cell Endocytic Vesicle Intracellular Transport Regulation Of Vesicle-mediated Transport GDP Binding Establishment Of Protein Localization Early Endosome Membrane Cellular Localization Regulation Of Transport Synaptic Vesicle Vesicle-mediated Transport Cytoplasmic Vesicle GTPase Activity Early Endosome Positive Regulation Of Myoblast Fusion Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Recycling Endosome Membrane Melanosome Endosomal Transport Endomembrane System Nucleotide Binding Endosome Membrane Intracellular Protein Transport Glutamatergic Synapse Positive Regulation Of Intracellular Transport Regulation Of Cellular Component Organization Azurophil Granule Membrane Lysosomal Membrane Regulation Of Dendritic Spine Development Perinuclear Region Of Cytoplasm Organelle Assembly Hydrolase Activity Positive Regulation Of Endocytic Recycling Plasma Membrane To Endosome Transport Regulation Of Synaptic Transmission, Glutamatergic Endocytic Recycling Positive Regulation Of Transport Cilium Assembly Regulation Of Intracellular Transport Organelle Organization Regulation Of Synaptic Vesicle Cycle Cilium Organization Regulation Of Synapse Organization Vesicle Organization
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