CENPK and MRFAP1L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CENPK	MRFAP1L1
Description		centromere protein K	Morf4 family associated protein 1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Chromosome Segregation Kinetochore Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Diverticular disease ( 30177863) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: AP1G2 HSPB1 MRFAP1L1 PCBD2 PEX14 RTN4IP1 SOX6 TRIM55 TRIM63 WASHC3	44 interacting genes: ABI1 ABI2 ABI3 BYSL C1orf216 C3orf62 CAGE1 CDK2AP1 CDK2AP2 CENPK CEP44 CNOT7 CSPP1 DRC4 EIF2B2 GTF2IRD1 HGS HTT IHO1 JAKMIP1 LMO2 LNX1 LNX2 MEOX2 MORF4L1 NTAQ1 OLIG2 PIH1D2 PIK3R2 PSMA1 RADIL RDM1 SDCBP SFR1 SMARCE1 SYCE1 TCF4 TEX11 TMEM126B TSNAX TXN2 UBTD1 ZDHHC17 ZNF417
Entrez ID		64105	114932
HPRD ID		13323	15162
Ensembl ID		ENSG00000123219	ENSG00000178988
Uniprot IDs		D6RHD3 D6RJF0 Q9BS16	A0A075DDR2 Q96HT8
PDB IDs		7PB4 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Contractile Muscle Fiber	Actin-based Cell Projection SCAR Complex Protein Binding
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