GPSM3 and KCNJ5-AS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPSM3	KCNJ5-AS1
Description		G protein signaling modulator 3	KCNJ5 antisense RNA 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane	Extracellular Region
	Molecular Function	Protein Binding GTPase Regulator Activity	Protein Binding
	Biological Process	Positive Regulation Of Leukocyte Chemotaxis Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		G alpha (i) signalling events
Drugs
Diseases
GWAS		A body shape index ( 34021172) Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		44 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KCNJ5-AS1 KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPMIP5 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 ZNF20 ZNF581	7 interacting genes: APP EFHC1 FBXO44 FRS3 GPSM3 PLEKHF2 TLX3
Entrez ID		63940	219833
HPRD ID		13605	11344
Ensembl ID		ENSG00000213654	ENSG00000174370
Uniprot IDs		A0A024RCP6 Q9Y4H4
PDB IDs
Enriched GO Terms of Interacting Partners?		Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Central Nervous System Development Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Positive Regulation Of Chemotaxis Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Positive Regulation Of Leukocyte Chemotaxis Lipoprotein Particle Growth Factor Receptor Binding Main Axon Positive Regulation Of Leukocyte Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Early Endosome Membrane Regulation Of Chemotaxis Heparan Sulfate Binding Signaling Receptor Activator Activity
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