HIGD1C and MTERF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HIGD1C	MTERF3
Description		HIG1 hypoxia inducible domain family member 1C	mitochondrial transcription termination factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding Nucleic Acid Binding DNA Binding Protein Binding
	Biological Process	Response To Hypoxia Mitochondrial Respirasome Assembly	Regulation Of DNA-templated Transcription Ribosome Biogenesis Negative Regulation Of DNA-templated Transcription Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1	PINK1-PRKN Mediated Mitophagy rRNA modification in the mitochondrion Mitochondrial mRNA modification
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: APOC1 CIDEB CYB5R1 FARS2 GAD2 MTERF3 NTAQ1 PBX3 RBFA SYT16 TCEA2 TMEM14B TMEM31	28 interacting genes: ADGRE2 AGTRAP APOC1 APP ARL6IP1 CACFD1 CMTM5 ERG28 FADS6 FUNDC1 GPR108 HIGD1C MAL2 MIR34B PBX3 RHBDD2 SCAMP1 SLC17A9 SLC2A5 SLC50A1 STX8 SYNGR1 SYP TMEM14C UPF2 YIF1A ZDHHC21 ZFPL1
Entrez ID		613227	51001
HPRD ID		19625	10823
Ensembl ID		ENSG00000214511	ENSG00000156469
Uniprot IDs		A8MV81	E5RIK9 Q96E29
PDB IDs			3M66
Enriched GO Terms of Interacting Partners?		Very-low-density Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Regulation Of Triglyceride Metabolic Process Negative Regulation Of Phosphatidylcholine Catabolic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Protein-N-terminal Glutamine Amidohydrolase Activity Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Protein-N-terminal Asparagine Amidohydrolase Activity	Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Apparatus Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Endoplasmic Reticulum Very-low-density Lipoprotein Particle Vesicle-mediated Transport Golgi Membrane
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