MTERF3 and FUNDC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		MTERF3	FUNDC1
Description		mitochondrial transcription termination factor 3	FUN14 domain containing 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Cytosol	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding Nucleic Acid Binding DNA Binding Protein Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Ribosome Biogenesis Negative Regulation Of DNA-templated Transcription Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription	Autophagy Of Mitochondrion Mitophagy Response To Hypoxia Autophagy Mitochondrial Fusion
Pathways		PINK1-PRKN Mediated Mitophagy rRNA modification in the mitochondrion Mitochondrial mRNA modification	Receptor Mediated Mitophagy
Drugs
Diseases
GWAS			Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)
Interacting Genes		28 interacting genes: ADGRE2 AGTRAP APOC1 APP ARL6IP1 CACFD1 CMTM5 ERG28 FADS6 FUNDC1 GPR108 HIGD1C MAL2 MIR34B PBX3 RHBDD2 SCAMP1 SLC17A9 SLC2A5 SLC50A1 STX8 SYNGR1 SYP TMEM14C UPF2 YIF1A ZDHHC21 ZFPL1	15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1
Entrez ID		51001	139341
HPRD ID		10823	06658
Ensembl ID		ENSG00000156469	ENSG00000069509
Uniprot IDs		E5RIK9 Q96E29	Q8IVP5
PDB IDs		3M66	2N9X 5GMV
Enriched GO Terms of Interacting Partners?		Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Apparatus Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Endoplasmic Reticulum Very-low-density Lipoprotein Particle Vesicle-mediated Transport Golgi Membrane	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Membrane Autophagy Of Mitochondrion Autophagosome Maturation Autophagy Mitophagy Cellular Response To Starvation Mitochondrial Outer Membrane Autophagosome Response To Starvation Autophagosome Assembly Autophagosome Organization Cellular Response To Nutrient Levels Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Vacuole Organization Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Response To Nutrient Levels White Fat Cell Differentiation GABA Receptor Binding Ubiquitin Protein Ligase Binding Viral Genome Replication Fat Cell Differentiation Mitochondrion Organelle Assembly NAD Binding Cytoplasmic Vesicle Beta-tubulin Binding Transcription Coregulator Binding Catabolic Process Membrane Fission Organelle Membrane Protein-containing Complex Organization Transcription Corepressor Binding Protein Localization To Vacuolar Membrane Microtubule Binding Cellular Response To Amino Acid Starvation Transcription Repressor Complex Response To Amino Acid Starvation Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Mitochondrial Membrane Fission Cellular Component Assembly Positive Regulation Of Membrane Tubulation Microtubule Delta(3)-delta(2)-enoyl-CoA Isomerase Activity Retromer, Tubulation Complex Leptin Receptor Binding
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