RINT1 and SFR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RINT1	SFR1
Description		RAD50 interactor 1	SWI5 dependent homologous recombination repair protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Dsl1/NZR Complex	Nucleus Nucleoplasm Nucleolus Centrosome Swi5-Sfr1 Complex
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Mitotic G2 DNA Damage Checkpoint Signaling Protein Transport Vesicle-mediated Transport Regulation Of ER To Golgi Vesicle-mediated Transport	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Positive Regulation Of DNA-templated Transcription Cellular Response To Estrogen Stimulus
Pathways		COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS
Interacting Genes		101 interacting genes: AIRIM ANKRD11 ARHGAP45 ARNT2 BFSP2 BLOC1S6 BNIP3L C19orf44 C1orf35 CCDC120 CCDC121 CCDC146 CCDC187 CCDC57 CCDC88B CCHCR1 CDR2L CEP57L1 CSPP1 CWF19L2 DCTN2 DCX DPF2 DRC4 EPC1 ESRRG EXOC8 FAM107A FAM110A FAM124B FAM161A FAM161B FAM81B FAM90A1 FANCG FCHSD2 GFI1B GRAP2 HDAC4 HGS INPP5J JMY KIAA1217 KRT1 LMO2 LSP1P3 LYSMD1 MBD3 MCM7 MISP MYOZ3 NAB2 NFIL3 PCM1 PIK3R2 PIMREG PRPF18 PRPF31 PSTPIP1 RAD50 RAMAC RB1 RBL1 RBL2 RBM41 RIBC1 RNF39 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN SUOX TACO1 TEX9 TRIM69 TSEN54 TSHZ2 TSHZ3 TXLNA USHBP1 UTP14C VAV3 VPS37C XPNPEP1 ZBTB16 ZC2HC1C ZNF648 ZNF655 ZNF688 ZNF697 ZNF835 ZSCAN5B ZW10	14 interacting genes: CDC5L CEP70 DTNBP1 EXOC1 FBXO7 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 SWI5 TFIP11 TRAF3IP1
Entrez ID		60561	119392
HPRD ID		15250	12590
Ensembl ID		ENSG00000135249	ENSG00000156384
Uniprot IDs		Q6NUQ1	Q86XK3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoskeleton Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition Microtubule Cytoskeleton Organization Microtubule-based Process Centrosome SWI/SNF Complex Negative Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition NBAF Complex Nuclear Speck Negative Regulation Of Cell Cycle Process Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Double-strand Break Repair Microtubule Anchoring Centriole Protein Localization To Centrosome Regulation Of Sister Chromatid Segregation Cytoskeleton Organization Nucleoplasm Regulation Of Nucleotide-excision Repair Microtubule Binding	Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Process Telomere Maintenance Negative Regulation Of Interferon-beta Production Negative Regulation Of Cell Cycle Chromosome Organization Centrosome Telomere Organization DNA Metabolic Process Regulation Of Cell Cycle Process Identical Protein Binding DNA Damage Response Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Cell Cycle Phase Transition Chromosome, Telomeric Region Cytoplasm Response To Glucoside Negative Regulation Of Type I Interferon Production Kinetochore Adaptor Activity Negative Regulation Of Mitotic Cell Cycle Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Telomere-telomerase Complex Assembly Regulation Of Interferon-beta Production Regulation Of Cell Cycle Cilium Assembly Response To Stress Meiosis I Cell Cycle Process Mitotic Recombination-dependent Replication Fork Processing DNA Strand Exchange Activity Cellular Response To Ionizing Radiation Presynaptic Intermediate Filament Cytoskeleton G2/MI Transition Of Meiotic Cell Cycle Spliceosomal Complex Disassembly Cilium Organization Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Swi5-Sfr1 Complex Organelle Organization Negative Regulation Of Cellular Component Organization Catalytic Step 2 Spliceosome Nuclear Division Positive Regulation Of Protein K48-linked Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Organelle Assembly U2-type Post-mRNA Release Spliceosomal Complex Lewy Body Core Dsl1/NZR Complex
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