SFR1 and EXOC1

Number of citations of the paper that reports this interaction (PubMedID 17043677)
0

Data Source:
BioGRID (two hybrid)

		SFR1	EXOC1
Description		SWI5 dependent homologous recombination repair protein 1	exocyst complex component 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Centrosome Swi5-Sfr1 Complex	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body
	Molecular Function	Transcription Coactivator Activity Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Positive Regulation Of DNA-templated Transcription Cellular Response To Estrogen Stimulus	Mitotic Cytokinesis Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport Regulation Of Macroautophagy Defense Response To Virus Membrane Fission Vesicle Tethering Involved In Exocytosis
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: CDC5L CEP70 DTNBP1 EXOC1 FBXO7 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 SWI5 TFIP11 TRAF3IP1	29 interacting genes: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST ITSN1 KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNCA SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIO
Entrez ID		119392	55763
HPRD ID		12590	07615
Ensembl ID		ENSG00000156384	ENSG00000090989
Uniprot IDs		Q86XK3	Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Process Telomere Maintenance Negative Regulation Of Interferon-beta Production Negative Regulation Of Cell Cycle Chromosome Organization Centrosome Telomere Organization DNA Metabolic Process Regulation Of Cell Cycle Process Identical Protein Binding DNA Damage Response Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Cell Cycle Phase Transition Chromosome, Telomeric Region Cytoplasm Response To Glucoside Negative Regulation Of Type I Interferon Production Kinetochore Adaptor Activity Negative Regulation Of Mitotic Cell Cycle Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Telomere-telomerase Complex Assembly Regulation Of Interferon-beta Production Regulation Of Cell Cycle Cilium Assembly Response To Stress Meiosis I Cell Cycle Process Mitotic Recombination-dependent Replication Fork Processing DNA Strand Exchange Activity Cellular Response To Ionizing Radiation Presynaptic Intermediate Filament Cytoskeleton G2/MI Transition Of Meiotic Cell Cycle Spliceosomal Complex Disassembly Cilium Organization Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Swi5-Sfr1 Complex Organelle Organization Negative Regulation Of Cellular Component Organization Catalytic Step 2 Spliceosome Nuclear Division Positive Regulation Of Protein K48-linked Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Organelle Assembly U2-type Post-mRNA Release Spliceosomal Complex Lewy Body Core Dsl1/NZR Complex	Microtubule Binding Microtubule-based Process Cytoskeleton Organelle Organization Phosphatidylinositol 3-kinase Inhibitor Activity Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Cellular Localization Cell Leading Edge Cell Projection Cytoskeleton Organization Positive Regulation Of Cell Size Regulation Of Cytoskeleton Organization Microtubule Molecular Adaptor Activity Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cell Projection Organization Actin Binding Cytoplasmic Vesicle Positive Regulation Of Cellular Component Organization Guanyl-nucleotide Exchange Factor Activity Intracellular Transport Regulation Of Organelle Organization Phagophore Assembly Site Membrane Establishment Of Localization In Cell Signal Transduction Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Regulation Of Synapse Organization Response To Desipramine Negative Regulation Of Norepinephrine Uptake Negative Regulation Of Protein-containing Complex Assembly Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Microtubule-based Process Negative Regulation Of Cellular Component Organization Phagophore Assembly Site Ribophagy Protein-membrane Adaptor Activity Extrinsic Component Of Phagophore Assembly Site Membrane Positive Regulation Of Neuroblast Proliferation Lamellipodium Assembly Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Lamellipodium Assembly Involved In Ameboidal Cell Migration Regulation Of Endocytosis Positive Regulation Of Axon Extension
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