HAPLN2 and PNMA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HAPLN2	PNMA2
Description		hyaluronan and proteoglycan link protein 2	PNMA family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Node Of Ranvier Synapse Perineuronal Net	Nucleus Nucleolus
	Molecular Function	Protein Binding Hyaluronic Acid Binding	Protein Binding
	Biological Process	Skeletal System Development Cell Adhesion Central Nervous System Development Establishment Of Blood-nerve Barrier Extracellular Matrix Assembly	Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		47 interacting genes: ASB13 BANP CCDC125 CIDEB EXOSC8 FHL3 FHL5 FNDC3B GOLGA6L9 GPRIN2 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT40 KRT85 KRTAP10-8 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP6-2 KRTAP6-3 KRTAP9-2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OIP5 PFDN5 PM20D2 PNMA1 PNMA2 PPP1R16B PSTPIP1 SEC13 SSC4D TFCP2 TRIM23 TRIM27 VWC2 ZMYND12 ZNF438 ZNF655	34 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 DDX21 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 LYN MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RSPH1 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688
Entrez ID		60484	10687
HPRD ID		17088	04915
Ensembl ID		ENSG00000132702	ENSG00000240694
Uniprot IDs		B7Z1R1 Q9GZV7	Q5U5Z3 Q9UL42
PDB IDs			8UYO
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Identical Protein Binding Cytoskeleton Organization Epidermis Development Keratinization Negative Regulation Of Viral Transcription COPII Vesicle Coat Suppression Of Viral Release By Host Protein Binding COPII-coated Vesicle Cargo Loading Regulation Of Viral Transcription Cytosol Cytoskeleton	Nucleus
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