PNMA2 and MORF4L2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PNMA2	MORF4L2
Description		PNMA family member 2	mortality factor 4 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus	Nucleosome Nucleus Nucleoplasm Nucleolus Plasma Membrane NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Apoptotic Process	DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription DNA Damage Response Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)	Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494)
Interacting Genes		34 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 DDX21 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 LYN MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RSPH1 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688	55 interacting genes: AMOTL2 ARID3A BCL11A BEND7 BEX5 CAMK2B CDR2 CEP55 DDIT4L DISC1 DSCAM EVI5 FAM9B FBXO16 GLA GOLGA2 GPBP1 GRAMD2B HDAC1 HMBOX1 HOMEZ HUNK IKZF1 KCTD1 KLHL3 L3MBTL3 LUZP4 LZTS2 MEOX2 MRFAP1 MRGBP MRPL12 NAB2 PHC2 PIBF1 PICK1 PNMA2 POU6F2 RB1 REL SIN3A SYN3 THAP1 TLE1 TLE5 TNIP1 TNNT2 TRIM41 TSN ZBTB10 ZBTB14 ZBTB26 ZBTB43 ZBTB7B ZNF48
Entrez ID		10687	9643
HPRD ID		04915	02326
Ensembl ID		ENSG00000240694	ENSG00000123562
Uniprot IDs		Q5U5Z3 Q9UL42	Q15014
PDB IDs		8UYO
Enriched GO Terms of Interacting Partners?		Nucleus	Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Transcription Corepressor Activity Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Nucleoplasm Regulation Of Axon Extension RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Importin-alpha Family Protein Binding Positive Regulation Of Cell Development Positive Regulation Of Neurogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Neurogenesis
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