ZNF350 and DYRK3

Number of citations of the paper that reports this interaction (PubMedID 36585413)
42

Data Source:
BioGRID (two hybrid)

		ZNF350	DYRK3
Description		zinc finger protein 350	dual specificity tyrosine phosphorylation regulated kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix Nuclear Body Transcription Repressor Complex	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Stress Granule Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Protein Phosphorylation Erythrocyte Differentiation Nuclear Speck Organization Stress Granule Disassembly Negative Regulation Of Apoptotic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Division Regulation Of Cellular Response To Stress Positive Regulation Of Cell Cycle G2/M Phase Transition Organelle Disassembly Regulation Of TORC1 Signaling
Pathways		Generic Transcription Pathway SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Tourette syndrome ( 30818990)	Mean corpuscular volume ( 32888494)
Interacting Genes		9 interacting genes: ATF7IP BRCA1 DYRK3 FBXL17 NEK1 RCAN1 RNF11 TIAM1 USP21	12 interacting genes: ACAA2 ADAM22 DNAJA2 DNAJB1 FBXO25 GORASP2 MAGI2 NEDD4L PGM1 PRNP SNAPIN ZNF350
Entrez ID		59348	8444
HPRD ID		05663	04607
Ensembl ID		ENSG00000256683	ENSG00000143479
Uniprot IDs		Q9GZX5	O43781
PDB IDs			5Y86
Enriched GO Terms of Interacting Partners?		Protein Modification Process Pericentriolar Material Epigenetic Regulation Of Gene Expression Post-translational Protein Modification Protein Autoubiquitination Organelle Disassembly Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex	Protein-folding Chaperone Binding
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