CARD18 and CARD17P

Number of citations of the paper that reports this interaction (PubMedID 15383541)
0

Data Source:
HPRD (in vivo, in vitro)

		CARD18	CARD17P
Description		caspase recruitment domain family member 18	caspase recruitment domain family member 17, pseudogene
Image			No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex	Cytoplasm Protein-containing Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Peptidase Inhibitor Activity CARD Domain Binding Caspase Binding	Cysteine-type Endopeptidase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Peptidase Inhibitor Activity Identical Protein Binding Caspase Binding
	Biological Process	Proteolysis Inflammatory Response Negative Regulation Of Protein Binding Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-1 Beta Production Regulation Of Apoptotic Process	Proteolysis Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-1 Beta Production Regulation Of Apoptotic Process Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: CARD17P CARD8 DYNC2H1	3 interacting genes: CARD16 CARD18 CASP1
Entrez ID		59082	440068
HPRD ID		16099	17149
Ensembl ID		ENSG00000255501
Uniprot IDs		P57730
PDB IDs		1DGN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-1 Production Regulation Of Interleukin-1 Beta Production Regulation Of Interleukin-1 Production CARD8 Inflammasome Complex NACHT Domain Binding Proteolysis CARD8 Inflammasome Complex Assembly Protein Maturation Negative Regulation Of Cytokine Production NLRP3 Inflammasome Complex Negative Regulation Of NLRP3 Inflammasome Complex Assembly Self Proteolysis Canonical Inflammasome Complex Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway CARD Domain Binding Pyroptotic Cell Death Cysteine-type Endopeptidase Activator Activity Intraciliary Retrograde Transport Minus-end-directed Microtubule Motor Activity Caspase Binding Cytoplasmic Dynein Complex Spinal Cord Motor Neuron Differentiation Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Lipopolysaccharide-mediated Signaling Pathway Canonical Inflammasome Complex Assembly Protein-containing Complex Protein Metabolic Process Dynein Intermediate Chain Binding 9+2 Motile Cilium Dynein Light Intermediate Chain Binding Dynein Complex Coronary Vasculature Development Cysteine-type Endopeptidase Inhibitor Activity Regulation Of Cytokine Production Pattern Recognition Receptor Activity Cell Differentiation In Spinal Cord Positive Regulation Of Smoothened Signaling Pathway Pyroptotic Inflammatory Response Regulation Of NLRP3 Inflammasome Complex Assembly Ciliary Tip Intraciliary Transport Molecular Condensate Scaffold Activity	CARD Domain Binding Protease Inhibitor Complex Cysteine-type Endopeptidase Activity Regulation Of Interleukin-1 Beta Production Regulation Of Interleukin-1 Production Caspase Binding Negative Regulation Of Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Interleukin-1 Beta Production Enzyme Binding Negative Regulation Of Interleukin-1 Production Regulation Of Protein Binding Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein-containing Complex Regulation Of Cytokine Production Kinase Binding Peptidase Inhibitor Activity Cellular Response To Lipopolysaccharide Proteolysis Regulation Of Cytokine-mediated Signaling Pathway AIM2 Inflammasome Complex Assembly Cellular Response To Molecule Of Bacterial Origin AIM2 Inflammasome Complex IPAF Inflammasome Complex Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Cytokine Precursor Processing Response To Lipopolysaccharide NLRP1 Inflammasome Complex Regulation Of Canonical NF-kappaB Signal Transduction Response To Molecule Of Bacterial Origin Negative Regulation Of Cytokine Production Osmosensory Signaling Pathway NLRP3 Inflammasome Complex Positive Regulation Of Interleukin-18 Production Negative Regulation Of Macromolecule Biosynthetic Process Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Cellular Response To Lipid Negative Regulation Of Biosynthetic Process Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Interleukin-18 Production Canonical Inflammasome Complex Interleukin-18-mediated Signaling Pathway Pyroptotic Cell Death Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Inflammatory Response Protein Poly-ADP-ribosylation Negative Regulation Of Macromolecule Metabolic Process Protein Autoprocessing
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